Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6
Interactor 2: KREM1 (Q96MU8)
Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)
Gene: KREMEN1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27524201 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CUB~FXa_inhibition, CUB~Ldl_recept_a |
| Common GO terms | GO:0005886 - plasma membrane GO:0016055 - Wnt signaling pathway GO:0043025 - neuronal cell body |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025