Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: DHX40 (Q8IX18)
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD)
Gene: DHX40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRR2_plug~Helicase_C, DEAD~DEAD, DEAD~HA2_N, DEAD~Helicase_C, HA2_C~Helicase_C, HA2_N~Helicase_C, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, DEAD~Sec63, Helicase_C~Sec63
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005681 - spliceosomal complex
GO:0016887 - ATP hydrolysis activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2136
Hs

1 779
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Last updated: 11Aug2025