HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	35384245, 36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 976
+	Hs
		296503 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA7_HUMAN (4-974): 0: 1120: 50.15
+	Hs
		296471 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA5_HUMAN (11-976): 0: 1115: 51.34
+	Hs
		296472 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA4_HUMAN (1-974): 0: 1110: 50.35
+	Hs
		296445 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA3_HUMAN (24-976): 0: 1096: 50.98
+	Hs
		296588 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA6_HUMAN (9-973): 0: 1071: 47.70
+	Hs
		710407 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		EPHA2_HUMAN (1-976): 0: 1124: 100.00
+	Hs
		931879 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		EPHA5_HUMAN (11-976): 0: 1115: 51.34
+	Hs
		296446 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA8_HUMAN (28-975): 0: 1037: 46.72
+	Hs
		710739 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		EPHA8_HUMAN (28-975): 0: 1037: 46.72
+	Hs
		931906 GGA3_HUMAN (1-510): 2.44e-56: 202: 15.73		EPHA5_HUMAN (11-976): 0: 1115: 51.34
+	Hs
		710667 GGA3_HUMAN (1-510): 2.44e-56: 202: 15.73		EPHA3_HUMAN (24-976): 0: 1096: 50.98
+	Hs
		710840 ITSN1_HUMAN (188-414): 1.92e-46: 176: 22.50		EPHB2_HUMAN (28-973): 0: 1077: 48.29
+	Hs
		296438 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		FGFR3_HUMAN (381-889): 3.37e-136: 430: 24.65
+	Hs
		650332 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		FGFR3_HUMAN (381-889): 3.37e-136: 430: 24.65
+	Rn
		81626 B5DFM1_RAT (6-497): 1.24e-58: 203: 16.53		INSR_RAT (371-873): 1.87e-134: 440: 29.49
+	Hs
		465671 GGA3_HUMAN (1-510): 2.44e-56: 202: 15.73		IGF1R_HUMAN (393-877): 1.45e-133: 437: 29.90
+	Hs
		169391 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		INSR_HUMAN (281-911): 2.91e-136: 444: 24.78
+	Hs
		290231 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		LYN_HUMAN (607-879): 2.07e-64: 228: 42.91
+	Hs
		463510 SPTN1_HUMAN (103-481): 1.46e-55: 203: 14.59		LYN_HUMAN (607-879): 2.07e-64: 228: 42.91
+	Hs
		463538 ITSN1_HUMAN (188-414): 1.92e-46: 176: 22.50		LYN_HUMAN (607-879): 2.07e-64: 228: 42.91