HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: EPHA6 (Q9UF33)
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)
Gene: EPHA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.578

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 1036
+	Hs
		296503 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA7_HUMAN (15-1036): 0: 1206: 55.86
+	Hs
		296472 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA4_HUMAN (15-1036): 0: 1184: 56.88
+	Hs
		296471 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA5_HUMAN (11-1028): 0: 1183: 56.57
+	Hs
		296445 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA3_HUMAN (24-1028): 0: 1180: 59.88
+	Hs
		931879 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		EPHA5_HUMAN (11-1028): 0: 1183: 56.57
+	Hs
		296446 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA8_HUMAN (34-1036): 0: 1104: 52.54
+	Hs
		296444 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		EPHA2_HUMAN (31-1036): 0: 1054: 46.59
+	Hs
		710739 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		EPHA8_HUMAN (34-1036): 0: 1104: 52.54
+	Hs
		710407 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		EPHA2_HUMAN (31-1036): 0: 1054: 46.59
+	Hs
		296435 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		FGFR2_HUMAN (378-982): 1.28e-151: 472: 20.92
+	Hs
		296438 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		FGFR3_HUMAN (382-986): 1.52e-151: 472: 19.91
+	Hs
		296429 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		FGFR1_HUMAN (382-968): 4.18e-148: 463: 20.35
+	Hs
		641227 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		FGFR2_HUMAN (378-982): 1.28e-151: 472: 20.92
+	Hs
		650332 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		FGFR3_HUMAN (382-986): 1.52e-151: 472: 19.91
+	Hs
		541620 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		FGFR1_HUMAN (382-968): 4.18e-148: 463: 20.35
+	Hs
		541747 GGA1_HUMAN (2-516): 2.51e-62: 217: 14.50		FGFR1_HUMAN (382-968): 4.18e-148: 463: 20.35
+	Hs
		541721 GGA3_HUMAN (1-510): 2.44e-56: 202: 15.73		FGFR1_HUMAN (382-968): 4.18e-148: 463: 20.35
+	Hs
		465671 GGA3_HUMAN (1-510): 2.44e-56: 202: 15.73		IGF1R_HUMAN (388-932): 6.13e-132: 434: 26.92
+	Hs
		290229 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		FYN_HUMAN (625-931): 3.79e-59: 214: 37.99
+	Hs
		290233 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		SRC_HUMAN (623-931): 3.43e-59: 214: 40.32