HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: UBS3A (P57075)
Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1)
Gene: UBASH3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 964 Hs			1 661
+	Hs
		571911 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		UBS3A_HUMAN (1-661): 0: 1048: 100.00
+	Hs
		943814 TRIM5_HUMAN (1-459): 4.72e-67: 235: 17.11		UBS3A_HUMAN (1-661): 0: 1048: 100.00
+	Hs
		943792 TRI50_HUMAN (1-456): 2.56e-58: 210: 16.49		UBS3A_HUMAN (1-661): 0: 1048: 100.00
+	Hs
		1254791 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		UBS3B_HUMAN (1-655): 0: 904: 43.07
+	Hs
		571979 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		LASP1_HUMAN (163-337): 3.89e-36: 138: 17.11
+	Ce
		110366 NHL1_CAEEL (4-476): 3.13e-70: 254: 16.67		SRBS1_CAEEL (198-338): 3.32e-25: 113: 23.03
+	Hs
		302140 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		NEBL_HUMAN (188-340): 7.63e-29: 124: 20.12
+	Hs
		250202 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		VINEX_HUMAN (202-339): 5.69e-28: 121: 22.86
+	Hs
		1133109 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		LASP1_HUMAN (163-337): 3.89e-36: 138: 17.11
+	Hs
		987957 TRI39_HUMAN (6-459): 1.76e-70: 245: 16.67		GRB2_HUMAN (245-341): 1.32e-22: 98.4: 25.25
+	Hs
		1046423 TRI39_HUMAN (6-459): 1.76e-70: 245: 16.67		UBXN1_HUMAN (22-81): 1.06e-21: 98: 43.55
+	Hs
		571924 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		GRB2_HUMAN (245-341): 1.32e-22: 98.4: 25.25
+	Hs
		250278 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		VINEX_HUMAN (202-339): 5.69e-28: 121: 22.86
+	Hs
		635535 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		NEBU_HUMAN (187-337): 3.34e-22: 104: 18.41
+	Hs
		987723 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		GRB2_HUMAN (245-341): 1.32e-22: 98.4: 25.25
+	Hs
		1046378 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		UBXN1_HUMAN (22-81): 1.06e-21: 98: 43.55
+	Hs
		1256273 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		CD2AP_HUMAN (155-343): 1.01e-12: 73.3: 18.75