HitPredict

Interactor 1: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Interactor 2: AKAP6 (Q13023)
A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
Gene: AKAP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0060090 - molecular adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3336 Hs			1 2319
+	Hs
		340170 PCNT_HUMAN (1-3336): 0: 724: 100.00		CEP68_HUMAN (384-901): 2.45e-90: 314: 18.25
+	Hs
		340125 PCNT_HUMAN (1-3336): 0: 724: 100.00		SPTN1_HUMAN (913-1371): 1.08e-24: 115: 12.58
+	Hs
		340109 PCNT_HUMAN (1-3336): 0: 724: 100.00		SPTB2_HUMAN (620-1335): 1.01e-21: 106: 8.79
+	Hs
		174680 PCNT_HUMAN (1-3336): 0: 724: 100.00		SPTN2_HUMAN (841-1378): 1.02e-19: 99.7: 11.25
+	Hs
		340263 PCNT_HUMAN (1-3336): 0: 724: 100.00		MACF1_HUMAN (492-1261): 3.47e-11: 71.5: 10.78
+	Hs
		340185 PCNT_HUMAN (1-3336): 0: 724: 100.00		SYNE1_HUMAN (723-1252): 8.66e-11: 70.3: 12.82
+	Hs
		340110 PCNT_HUMAN (1-3336): 0: 724: 100.00		DYST_HUMAN (803-1297): 5.81e-09: 64.2: 11.73
+	Hs
		547448 GOGB1_HUMAN (1-2226): 4.03e-75: 283: 11.71		DMD_HUMAN (790-1253): 7.98e-19: 96.9: 14.08
+	Hs
		174801 AKAP9_HUMAN (1257-3327): 4.64e-45: 184: 9.63		SPTN2_HUMAN (841-1378): 1.02e-19: 99.7: 11.25
+	Hs
		772991 CP250_HUMAN (1961-3336): 3.16e-40: 167: 10.25		MYH9_HUMAN (809-1373): 1.05e-19: 99.3: 11.21
+	Hs
		772645 MYH10_HUMAN (2-997): 9.22e-37: 156: 9.17		MYH9_HUMAN (809-1373): 1.05e-19: 99.3: 11.21
+	Hs
		1035503 CENPE_HUMAN (1-1045): 1.04e-26: 123: 10.06		SPTN1_HUMAN (913-1371): 1.08e-24: 115: 12.58
+	Hs
		772647 MYH11_HUMAN (1-775): 2.47e-31: 138: 10.67		MYH9_HUMAN (809-1373): 1.05e-19: 99.3: 11.21
+	Dm
		561580 LVA_DROME (2315-3336): 7.1e-25: 117: 12.83		SPTCA_DROME (918-1371): 7.01e-26: 119: 12.06
+	Hs
		1040365 CP250_HUMAN (1961-3336): 3.16e-40: 167: 10.25		DYST_HUMAN (803-1297): 5.81e-09: 64.2: 11.73
+	Hs
		1216681 CROCC_HUMAN (2070-3326): 4.13e-36: 154: 9.16		SYNE1_HUMAN (723-1252): 8.66e-11: 70.3: 12.82
+	Hs
		1134767 NUMA1_HUMAN (2158-3204): 1.27e-34: 149: 10.73		MACF1_HUMAN (492-1261): 3.47e-11: 71.5: 10.78
+	Mm
		547402 PLEC_MOUSE (1-1072): 1.16e-28: 129: 10.48		DMD_MOUSE (724-1259): 4.01e-16: 87.6: 12.09
+	Hs
		535958 MYH4_HUMAN (2-634): 2.8e-17: 92: 10.53		MYH3_HUMAN (465-1150): 6.76e-21: 103: 9.66
+	Hs
		772814 PLEC_HUMAN (1-678): 2.36e-15: 85.9: 10.20		MYH9_HUMAN (809-1373): 1.05e-19: 99.3: 11.21