HitPredict

Interactor 1: TBCD8 (O95759)
TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein)
Gene: TBC1D8

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Hs			1 227
+	Hs
		344401 TBCD8_HUMAN (1-1140): 0: 1098: 100.00		RND3_HUMAN (4-227): 5.97e-99: 289: 64.00
+	Hs
		344402 TBCD8_HUMAN (1-1140): 0: 1098: 100.00		RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08
+	Hs
		1155376 EVI5L_HUMAN (398-1080): 1.07e-117: 385: 16.16		RB11B_HUMAN (3-224): 3.03e-77: 233: 18.83
+	Hs
		976478 EVI5L_HUMAN (398-1080): 1.07e-117: 385: 16.16		RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08
+	Hs
		976687 RBGP1_HUMAN (323-981): 1.21e-94: 328: 17.18		RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08
+	Hs
		978047 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RHOB_HUMAN (5-185): 8.64e-92: 269: 45.86
+	Hs
		978268 TB10A_HUMAN (400-758): 3.33e-82: 279: 24.93		RHOB_HUMAN (5-185): 8.64e-92: 269: 45.86
+	Hs
		247144 TBCD4_HUMAN (367-884): 3.59e-82: 295: 18.10		RAB2B_HUMAN (3-224): 6.68e-78: 235: 20.09
+	Hs
		953480 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RAC3_HUMAN (8-182): 7.47e-79: 236: 42.86
+	Hs
		988411 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25
+	Hs
		976376 TBCD1_HUMAN (367-843): 2.5e-80: 288: 17.04		RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08
+	Os
		1209948 Q5SMT0_ORYSJ (266-743): 2.56e-81: 282: 15.91		Q84TA8_ORYSJ (4-224): 3.21e-78: 235: 20.27
+	Os
		1209947 Q5SMT0_ORYSJ (266-743): 2.56e-81: 282: 15.91		Q7XHP7_ORYSJ (4-223): 3.27e-77: 233: 19.91
+	Hs
		1155398 TBC14_HUMAN (366-772): 1.47e-79: 277: 17.74		RB11B_HUMAN (3-224): 3.03e-77: 233: 18.83
+	Hs
		976628 TBC14_HUMAN (366-772): 1.47e-79: 277: 17.74		RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08
+	Hs
		1195316 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RHOF_HUMAN (9-191): 9.2e-51: 165: 43.01
+	Hs
		910256 TBD2B_HUMAN (479-727): 3.25e-30: 131: 33.20		RND2_HUMAN (1-227): 6.72e-109: 314: 100.00
+	Ce
		113116 Q23419_CAEEL (488-731): 1.48e-31: 135: 31.64		G5EFC1_CAEEL (3-227): 5.79e-78: 235: 19.30
+	Ce
		1041912 Q23419_CAEEL (488-731): 1.48e-31: 135: 31.64		RAC1_CAEEL (8-194): 1.65e-77: 233: 42.78
+	Hs
		953762 TBD2B_HUMAN (479-727): 3.25e-30: 131: 33.20		RAC3_HUMAN (8-182): 7.47e-79: 236: 42.86