HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: CADM1 (Q9BY67)
Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Gene: CADM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 442
+	Hs
		349617 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CADM1_HUMAN (1-442): 2.03e-85: 270: 100.00
+	Hs
		348943 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		348808 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CADM4_HUMAN (45-442): 2.31e-72: 234: 34.93
+	Hs
		349330 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		350584 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		348671 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		349775 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		349043 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		350183 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		1070491 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		349572 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		348867 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		1070344 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		349539 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		348836 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		1070332 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		350455 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		350572 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ROBO2_HUMAN (6-364): 6.1e-15: 79.5: 12.94
+	Hs
		350416 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		350405 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TITIN_HUMAN (135-439): 9.8e-09: 59.9: 14.38