Interactor 1: O96989 (O96989)
CDC45L (Cell division cycle 45) (EG:BACR7A4.11 protein) (LD35753p)
Gene: Cdc45
Interactor 2: MCM5 (Q9VGW6)
DNA replication licensing factor Mcm5 (EC 3.6.4.12) (Minichromosome maintenance 5 protein) (DmMCM5)
Gene: MCM5
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.77 | 1.00 | 0.878 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11024168, 16798881, 20122406, unassigned4 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, experimental interaction detection |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0003688 - DNA replication origin binding GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0006270 - DNA replication initiation and 2 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
