HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: ASB4 (Q9Y574)
Ankyrin repeat and SOCS box protein 4 (ASB-4)
Gene: ASB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24337577
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin, Ank_4~Tubulin, Ank_4~Tubulin_C
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 426
+	Hs
		1037456 TBB3_HUMAN (1-444): 0: 714: 91.44		ASB4_HUMAN (1-426): 3.59e-96: 296: 100.00
+	Hs
		1046628 TBB2A_HUMAN (1-430): 0: 709: 96.28		ASB4_HUMAN (1-426): 3.59e-96: 296: 100.00
+	Hs
		428145 TBB5_HUMAN (1-429): 0: 714: 97.44		ANK2_HUMAN (15-407): 1.71e-84: 284: 16.53
+	Hs
		965103 TBB2A_HUMAN (1-430): 0: 709: 96.28		ANK2_HUMAN (15-407): 1.71e-84: 284: 16.53
+	Mm
		57384 TBB5_MOUSE (1-429): 0: 714: 97.44		A2AM57_MOUSE (9-407): 2.46e-61: 216: 15.73
+	Hs
		862023 TBB4B_HUMAN (1-427): 0: 713: 98.60		DAPK1_HUMAN (133-409): 1.92e-47: 176: 14.19
+	Hs
		1037393 TBB3_HUMAN (1-444): 0: 714: 91.44		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		428113 TBB5_HUMAN (1-429): 0: 714: 97.44		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		428431 TBB5_HUMAN (1-429): 0: 714: 97.44		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		883508 TBB3_HUMAN (1-444): 0: 714: 91.44		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		883476 TBB4B_HUMAN (1-427): 0: 713: 98.60		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		933974 TBB4B_HUMAN (1-427): 0: 713: 98.60		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		1313672 TBB2B_HUMAN (1-430): 0: 712: 96.74		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		883632 TBB2B_HUMAN (1-430): 0: 712: 96.74		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		1046578 TBB2A_HUMAN (1-430): 0: 709: 96.28		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		381154 TBB4A_HUMAN (1-427): 0: 709: 100.00		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		381300 TBB4A_HUMAN (1-427): 0: 709: 100.00		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		883510 TBB2A_HUMAN (1-430): 0: 709: 96.28		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		1037272 TBB3_HUMAN (1-444): 0: 714: 91.44		ASB18_HUMAN (3-249): 5.75e-21: 96.6: 18.01
+	Hs
		1037398 TBB3_HUMAN (1-444): 0: 714: 91.44		ASB8_HUMAN (79-213): 2.57e-09: 60.1: 31.62