Interactor 1: NF1 (Q04690)
Neurofibromin (Neurofibromatosis-related protein NF-1)
Gene: NF1

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000165 - MAPK cascade
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014009 - glial cell proliferation
GO:0060291 - long-term synaptic potentiation
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 2841
Mm

1 1730
+ Mm
+ Hs
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+ Hs
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+ Mm

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Last updated: 15 Jul 2024