HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: KDM4A (Q9V333)
Probable lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (Probable JmjC domain-containing histone demethylation protein 3A) (Probable [histone H3]-trimethyl-L-lysine(36) demethylase 4A) (Probable [histone H3]-trimethyl-L-lysine(9) demethylase 4A)
Gene: KDM4A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19061644
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 495
+	Hs
		273420 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM4A_HUMAN (10-465): 0: 576: 50.54
+	Hs
		273422 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM4A_HUMAN (10-465): 0: 576: 50.54
+	Hs
		273432 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM4A_HUMAN (10-465): 0: 576: 50.54
+	Hs
		322652 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM4B_HUMAN (4-386): 0: 541: 57.70
+	Hs
		322654 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM4B_HUMAN (4-386): 0: 541: 57.70
+	Hs
		322666 H3C_HUMAN (1-136): 5.27e-58: 177: 94.12		KDM4B_HUMAN (4-386): 0: 541: 57.70
+	Dm
		381721 H3_DROME (1-136): 6.24e-61: 185: 100.00		KDM4B_DROME (11-405): 0: 528: 62.96
+	Hs
		998802 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM4C_HUMAN (6-385): 4.41e-175: 521: 56.77
+	Hs
		1017205 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM4C_HUMAN (6-385): 4.41e-175: 521: 56.77
+	Hs
		1258941 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KDM4C_HUMAN (6-385): 4.41e-175: 521: 56.77
+	Sp
		489137 H31_SCHPO (1-136): 3.44e-59: 181: 91.91		LID2_SCHPO (38-327): 2.78e-70: 245: 19.29
+	Sp
		531215 H33_SCHPO (1-136): 7.73e-58: 177: 91.18		LID2_SCHPO (38-327): 2.78e-70: 245: 19.29
+	Hs
		1162031 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM5D_HUMAN (4-124): 1.43e-15: 82.1: 23.97
+	Hs
		998913 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM5B_HUMAN (14-124): 1.87e-14: 78.6: 21.62
+	Dm
		381737 H3_DROME (1-136): 6.24e-61: 185: 100.00		KDM5_DROME (9-124): 2.49e-15: 81.3: 26.72
+	Hs
		833746 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KDM5C_HUMAN (4-124): 2.81e-15: 80.9: 23.14
+	Hs
		711809 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM5A_HUMAN (14-124): 8.4e-14: 76.3: 21.43
+	Hs
		711810 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM5A_HUMAN (14-124): 8.4e-14: 76.3: 21.43
+	Hs
		711825 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM5A_HUMAN (14-124): 8.4e-14: 76.3: 21.43
+	Hs
		711829 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KDM5A_HUMAN (14-124): 8.4e-14: 76.3: 21.43