HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: KDM4B (Q9V6L0)
Probable lysine-specific demethylase 4B (EC 1.14.11.66) (Probable JmjC domain-containing histone demethylation protein 3B) (Probable [histone H3]-trimethyl-L-lysine(9) demethylase 4B)
Gene: KDM4B

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19061644
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 590
+	Hs
		322652 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM4B_HUMAN (8-369): 0: 552: 61.58
+	Hs
		322654 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM4B_HUMAN (8-369): 0: 552: 61.58
+	Hs
		322666 H3C_HUMAN (1-136): 5.27e-58: 177: 94.12		KDM4B_HUMAN (8-369): 0: 552: 61.58
+	Hs
		998802 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM4C_HUMAN (3-381): 0: 540: 58.79
+	Hs
		1017205 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM4C_HUMAN (3-381): 0: 540: 58.79
+	Hs
		1258941 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KDM4C_HUMAN (3-381): 0: 540: 58.79
+	Hs
		273420 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM4A_HUMAN (3-357): 1.31e-174: 524: 60.56
+	Hs
		273422 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM4A_HUMAN (3-357): 1.31e-174: 524: 60.56
+	Hs
		273432 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM4A_HUMAN (3-357): 1.31e-174: 524: 60.56
+	Dm
		381718 H3_DROME (1-136): 6.24e-61: 185: 100.00		KDM4A_DROME (2-400): 9.47e-175: 506: 63.12
+	Sp
		489137 H31_SCHPO (1-136): 3.44e-59: 181: 91.91		LID2_SCHPO (37-311): 3.41e-73: 257: 20.34
+	Sp
		531215 H33_SCHPO (1-136): 7.73e-58: 177: 91.18		LID2_SCHPO (37-311): 3.41e-73: 257: 20.34
+	Hs
		711809 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Hs
		998913 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM5B_HUMAN (5-90): 1.01e-14: 79.8: 26.74
+	Hs
		1162031 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM5D_HUMAN (5-51): 7.73e-15: 80.2: 38.30
+	Hs
		711810 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Hs
		711825 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Hs
		833746 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KDM5C_HUMAN (5-51): 6.87e-15: 80.6: 38.30
+	Hs
		711829 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Dm
		381737 H3_DROME (1-136): 6.24e-61: 185: 100.00		KDM5_DROME (4-51): 1.52e-14: 79.4: 43.75