HitPredict

Interactor 1: K1C18 (P05783)
Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)
Gene: KRT18

Interactor 2: VIME (P08670)
Vimentin
Gene: VIM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 30021884, 34079125, 37071682, 35575683, 39358380
Identification Methods proximity labelling technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005737 - cytoplasm
GO:0005815 - microtubule organizing center
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005882 - intermediate filament
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 430
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Service provided by Combinatics, Japan

Last updated: 11Aug2025