Interactor 1: ODPA (P08559)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: PDHA1

Interactor 2: PDK2 (Q15119)
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)
Gene: PDK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 34079125, 27505672
Identification Methods proximity labelling technology, protein kinase assay
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006006 - glucose metabolic process
GO:0045254 - pyruvate dehydrogenase complex
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 390
Hs

1 407
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Last updated: 15 Jul 2024