HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030424 - axon GO:0031175 - neuron projection development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 758
+	Hs
		496206 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496488 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581945 GFAP_RAT (80-465): 9.96e-128: 379: 61.66		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94169 GFAP_RAT (80-465): 9.96e-128: 379: 61.66		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		372929 GFAP_MOUSE (80-465): 2.2e-129: 383: 61.14		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		497096 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		422133 NFL_HUMAN (82-413): 4.58e-87: 278: 51.80		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		422332 NFM_HUMAN (9-412): 5.26e-84: 278: 46.44		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581925 AINX_RAT (82-422): 5.04e-93: 292: 55.49		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94148 AINX_RAT (82-422): 5.04e-93: 292: 55.49		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Rn
		581922 NFL_RAT (82-413): 1.95e-85: 273: 52.24		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94145 NFL_RAT (82-413): 1.95e-85: 273: 52.24		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Rn
		522304 NFM_RAT (95-412): 3.2e-80: 267: 49.84		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94135 NFM_RAT (95-412): 3.2e-80: 267: 49.84		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		440283 NFM_MOUSE (95-412): 8.63e-80: 266: 49.84		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		203197 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		203211 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		203200 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		422135 NFL_HUMAN (82-413): 4.58e-87: 278: 51.80		MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55
+	Rn
		562617 NFL_RAT (82-413): 1.95e-85: 273: 52.24		NFH_RAT (311-752): 2.44e-13: 76.2: 12.22