HitPredict

Interactor 1: RHO2 (P06781)
GTP-binding protein RHO2 (EC 3.6.5.2)
Gene: RHO2

Interactor 2: LRG1 (P35688)
Rho-GTPase-activating protein LRG1 (LIM-RhoGAP protein 1)
Gene: LRG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11591390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Sc			1 1017
+	Sc
		448520 RHO1_YEAST (1-185): 2.93e-89: 261: 52.88		LRG1_YEAST (1-1017): 0: 828: 100.00
+	Ce
		98436 RHO1_CAEEL (5-191): 5e-90: 263: 50.53		F0IWT2_CAEEL (379-944): 8.61e-77: 278: 15.77
+	Hs
		978145 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG12_HUMAN (454-935): 3.2e-72: 258: 14.95
+	Hs
		978288 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RGAP1_HUMAN (493-1016): 1.3e-73: 257: 15.34
+	Hs
		978083 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG17_HUMAN (504-1017): 8.97e-71: 255: 15.78
+	Hs
		539993 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		BCR_HUMAN (465-942): 3.13e-69: 254: 16.74
+	Hs
		978067 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG21_HUMAN (548-1009): 5.86e-69: 254: 15.67
+	Hs
		978336 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG35_HUMAN (450-977): 3.94e-68: 252: 12.67
+	Hs
		978051 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG29_HUMAN (486-1017): 3.39e-68: 251: 13.48
+	Hs
		977970 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		ABR_HUMAN (427-944): 2.24e-69: 250: 15.56
+	Hs
		978157 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG18_HUMAN (380-1005): 6.67e-69: 245: 15.36
+	Hs
		67648 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG32_HUMAN (690-1013): 6.99e-64: 239: 17.68
+	Mm
		988892 RAC1_MOUSE (8-192): 8.14e-79: 235: 43.92		BCR_MOUSE (465-942): 2.18e-69: 255: 16.94
+	Mm
		988887 RAC1_MOUSE (8-192): 8.14e-79: 235: 43.92		ABR_MOUSE (465-944): 2.51e-69: 250: 16.39
+	Sc
		448587 RHO2_YEAST (1-192): 6.29e-81: 240: 100.00		RGD1_YEAST (466-929): 1.71e-68: 244: 16.84
+	Mm
		988897 RAC1_MOUSE (8-192): 8.14e-79: 235: 43.92		RHG32_MOUSE (690-1013): 8.51e-64: 238: 17.68
+	Hs
		977958 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHG01_HUMAN (726-935): 8.55e-52: 190: 28.44
+	Mm
		988885 RAC1_MOUSE (8-192): 8.14e-79: 235: 43.92		RHG01_MOUSE (726-935): 4.5e-52: 191: 28.44
+	Gg
		878594 Q6LC82_CHICK (8-192): 8.14e-79: 235: 43.92		PAXI_CHICK (3-219): 9.39e-49: 184: 21.27
+	Hs
		978094 RHOB_HUMAN (5-192): 3.61e-89: 261: 51.55		RHGBA_HUMAN (723-960): 3.83e-13: 75.9: 27.73