HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: SF3A2 (Q15428)
Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62)
Gene: SF3A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 464
+	Hs
		1073740 HM20B_HUMAN (64-165): 1.22e-15: 76: 32.35		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1073715 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1311936 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		CHD7_HUMAN (76-458): 1.11e-43: 167: 15.25
+	Hs
		818550 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		CHD7_HUMAN (76-458): 1.11e-43: 167: 15.25
+	Hs
		881831 SOX10_HUMAN (4-98): 1.86e-21: 93.2: 14.74		CHD7_HUMAN (76-458): 1.11e-43: 167: 15.25
+	Hs
		1332326 SOX17_HUMAN (10-90): 2.4e-12: 67.1: 19.75		CHD7_HUMAN (76-458): 1.11e-43: 167: 15.25
+	Hs
		1300971 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		CHD7_HUMAN (76-458): 1.11e-43: 167: 15.25
+	Hs
		617376 SP100_HUMAN (25-178): 1.23e-34: 131: 87.66		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		449779 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		TITIN_HUMAN (290-460): 7.67e-09: 60.4: 18.50
+	Ce
		136646 SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80		RPB1_CAEEL (141-462): 4.41e-27: 117: 16.62
+	Hs
		1243837 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		KMT2C_HUMAN (73-462): 1.38e-16: 85.1: 12.59
+	Hs
		818266 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		KMT2C_HUMAN (73-462): 1.38e-16: 85.1: 12.59
+	Hs
		1243843 SOX17_HUMAN (10-90): 2.4e-12: 67.1: 19.75		KMT2C_HUMAN (73-462): 1.38e-16: 85.1: 12.59
+	Hs
		867119 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		SC24C_HUMAN (120-446): 3.28e-12: 70.8: 19.39