HitPredict

Interactor 1: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: TBR1 (Q16650)
T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56)
Gene: TBR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 773 Hs			1 682
+	Hs
		980617 TLE1_HUMAN (8-773): 0: 580: 86.27		TBR1_HUMAN (1-682): 0: 724: 100.00
+	Hs
		980761 TLE3_HUMAN (8-773): 0: 539: 80.90		TBR1_HUMAN (1-682): 0: 724: 100.00
+	Hs
		171019 TLE4_HUMAN (1-773): 0: 622: 100.00		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		980958 TLE4_HUMAN (1-773): 0: 622: 100.00		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		980849 TLE3_HUMAN (8-773): 0: 539: 80.90		TBX15_HUMAN (114-668): 2.6e-132: 404: 24.20
+	Hs
		171017 TLE1_HUMAN (8-773): 0: 580: 86.27		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		168131 TLE3_HUMAN (8-773): 0: 539: 80.90		TBX3_HUMAN (116-635): 2.95e-127: 395: 23.44
+	Hs
		980667 TLE1_HUMAN (8-773): 0: 580: 86.27		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		203427 TLE1_HUMAN (8-773): 0: 580: 86.27		TBX1_HUMAN (180-430): 2.23e-103: 322: 37.95
+	Hs
		171018 TLE3_HUMAN (8-773): 0: 539: 80.90		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		980911 TLE3_HUMAN (8-773): 0: 539: 80.90		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Dm
		558401 GROU_DROME (8-773): 1.23e-144: 443: 59.14		Q9VMR2_DROME (162-591): 8.5e-94: 303: 26.91
+	Hs
		1132995 Q5T3G3_HUMAN (8-237): 2.38e-122: 368: 76.03		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		1127614 Q5JSZ1_HUMAN (1-210): 4e-116: 351: 88.39		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		168132 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		TBX3_HUMAN (116-635): 2.95e-127: 395: 23.44
+	Hs
		171021 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Ce
		137679 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX2_CAEEL (187-563): 5.4e-100: 314: 29.55
+	Ce
		137656 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX1_CAEEL (204-395): 5.75e-95: 295: 44.85
+	Ce
		137670 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX12_CAEEL (177-463): 7.29e-91: 288: 34.75
+	Ce
		137681 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX9_CAEEL (201-467): 3.87e-88: 279: 31.73