Protein: DLK2
Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9)

Gene: DLK2
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q6UY11

Gene Ontology (top 5):
GO:0005112 - Notch binding
GO:0005509 - calcium ion binding
GO:0016020 - membrane
GO:0042802 - identical protein binding
GO:0045598 - regulation of fat cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376516

LDLR
Low-density lipoprotein receptor

2

7

High-throughput

0.811

High

857482

NOTC1
Neurogenic locus notch homolog protein 1

2

19

High-throughput

0.811

High

1233983

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

2

1

High-throughput

0.811

High

1250238

NOTC3
Neurogenic locus notch homolog protein 3

2

18

High-throughput

0.811

High

1022624

LRP2
Low-density lipoprotein receptor-related protein 2

1

5

High-throughput

0.691

High

1250228

LRP10
Low-density lipoprotein receptor-related protein 10

2

11

High-throughput

0.628

High

1250229

LRC8A
Volume-regulated anion channel subunit LRRC8A

2

4

High-throughput

0.628

High

1250235

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

9

High-throughput

0.628

High

1250240

ALG5
Dolichyl-phosphate beta-glucosyltransferase

2

1

High-throughput

0.628

High

1224739

RN213
E3 ubiquitin-protein ligase RNF213

2

0

High-throughput

0.602

High

1248613

LCLT1
Lysocardiolipin acyltransferase 1

2

0

High-throughput

0.602

High

1250230

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

0

High-throughput

0.602

High

912684

CTR2
Cationic amino acid transporter 2

2

6

High-throughput

0.574

High

1237938

LRC8E
Volume-regulated anion channel subunit LRRC8E

2

4

High-throughput

0.574

High

1250233

ZDH18
Palmitoyltransferase ZDHHC18

2

4

High-throughput

0.574

High

1250234

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

2

2

High-throughput

0.574

High

1250236

XPO7
Exportin-7

2

4

High-throughput

0.574

High

1250239

RBGP1
Rab GTPase-activating protein 1

2

6

High-throughput

0.574

High

85279

RBG10
Rab GTPase-activating protein 1-like, isoform 10

2

2

High-throughput

0.558

High

164591

TNPO2
Transportin-2

2

5

High-throughput

0.558

High

180542

PLS1
Phospholipid scramblase 1

1

2

High-throughput

0.541

High

898096

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

5

High-throughput

0.536

High

1083115

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.536

High

422385

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

1250227

ATL4
ADAMTS-like protein 4

1

8

High-throughput

0.494

High

1250231

KR412
Keratin-associated protein 4-12

1

4

High-throughput

0.494

High

50108

S22AN
Solute carrier family 22 member 23

1

4

High-throughput

0.489

High

273203

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

6

High-throughput

0.489

High

1105743

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

9

High-throughput

0.489

High

1250237

ZPI
Protein Z-dependent protease inhibitor

1

1

High-throughput

0.489

High

575147

IDE
Insulin-degrading enzyme

1

2

High-throughput

0.470

High

409427

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

1122267

SCRIB
Protein scribble homolog

1

5

Small-scale

0.437

High

1195629

Q4LE60
TNPO2 variant protein

1

5

High-throughput

0.407

High

1208984

RBG1L
Rab GTPase-activating protein 1-like

1

5

High-throughput

0.407

High

897040

MAP2
Methionine aminopeptidase 2

2

0

High-throughput

0.328

High

1103826

TARB1
tRNA

2

0

High-throughput

0.328

High

1250232

VEZA
Vezatin

2

0

High-throughput

0.328

High

827822

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025