Interactor 1: NOTCH (P07207)
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]
Gene: N

Interactor 2: SUDX (Q9Y0H4)
E3 ubiquitin-protein ligase Su(dx) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Su(dx)) (Protein suppressor of deltex)
Gene: Su(dx)

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 30213861, 15620650, 17656366
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~HECT
Common GO terms GO:0005737 - cytoplasm
GO:0007219 - Notch signaling pathway
GO:0008587 - imaginal disc-derived wing margin morphogenesis
GO:0016348 - imaginal disc-derived leg joint morphogenesis
GO:0048190 - wing disc dorsal/ventral pattern formation
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 2703
Dm

1 949
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

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Last updated: 11Aug2025