Protein: ITB4
Integrin beta-4 (GP150) (CD antigen CD104)

Gene: ITB4, ITGB4
Organism: Homo sapiens
Interactions: 100
UniProt ID: P16144

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0005178 - integrin binding
GO:0005604 - basement membrane
GO:0005730 - nucleolus
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

556415

ITA6
Integrin alpha-6

3

20

Small-scale

0.847

High

337879

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.789

High

556444

PLEC
Plectin

1

18

Small-scale

0.692

High

556440

ILK
Integrin-linked protein kinase

1

6

High-throughput

0.691

High

556466

CLC2B
C-type lectin domain family 2 member B

1

16

High-throughput

0.691

High

556492

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

13

High-throughput

0.691

High

556474

ERBIN
Erbin

1

1

Small-scale

0.680

High

556436

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.665

High

556484

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.656

High

556417

SHC1
SHC-transforming protein 1

1

19

Small-scale

0.647

High

556409

LOX12
Polyunsaturated fatty acid lipoxygenase ALOX12

2

1

Small-scale

0.632

High

528485

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.628

High

556435

DYST
Dystonin

1

20

Small-scale

0.621

High

556424

NEK4
Serine/threonine-protein kinase Nek4

1

9

High-throughput

0.618

High

556411

FLNA
Filamin-A

1

20

Small-scale

0.618

High

556413

CBL
E3 ubiquitin-protein ligase CBL

1

4

High-throughput

0.618

High

556416

ITA3
Integrin alpha-3

1

20

Small-scale

0.618

High

556422

CD151
CD151 antigen

2

20

Small-scale

0.611

High

66974

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.606

High

556414

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

3

High-throughput

0.606

High

556445

K1H1
Keratin, type I cuticular Ha1

2

7

High-throughput

0.606

High

556446

TRIP6
Thyroid receptor-interacting protein 6

2

7

High-throughput

0.606

High

556488

PLS4
Phospholipid scramblase 4

2

1

High-throughput

0.606

High

556490

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

18

High-throughput

0.606

High

484561

NT2NC
Notch homolog 2 N-terminal-like protein C

1

11

High-throughput

0.594

High

556494

COHA1
Collagen alpha-1(XVII) chain

2

4

Small-scale

0.586

High

556448

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.580

High

556456

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.580

High

556462

NT2NA
Notch homolog 2 N-terminal-like protein A

1

12

High-throughput

0.555

High

526740

MYF5
Myogenic factor 5

2

1

High-throughput

0.553

High

556423

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.553

High

556429

KR107
Keratin-associated protein 10-7

2

17

High-throughput

0.553

High

556430

KR108
Keratin-associated protein 10-8

2

19

High-throughput

0.553

High

556431

KR109
Keratin-associated protein 10-9

2

18

High-throughput

0.553

High

556437

KRA11
Keratin-associated protein 1-1

2

19

High-throughput

0.553

High

556455

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

9

High-throughput

0.553

High

556457

K1C40
Keratin, type I cytoskeletal 40

2

7

High-throughput

0.553

High

556461

ATL4
ADAMTS-like protein 4

2

1

High-throughput

0.553

High

556463

KRA13
Keratin-associated protein 1-3

2

19

High-throughput

0.553

High

556467

APBP2
Amyloid protein-binding protein 2

2

3

High-throughput

0.553

High

556479

KRA93
Keratin-associated protein 9-3

2

19

High-throughput

0.553

High

556480

KRA92
Keratin-associated protein 9-2

2

19

High-throughput

0.553

High

556481

KRA42
Keratin-associated protein 4-2

2

19

High-throughput

0.553

High

556482

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

556441

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.553

High

253687

SDC3
Syndecan-3

1

16

Small-scale

0.552

High

556410

SDC1
Syndecan-1

1

7

Small-scale

0.552

High

318349

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.536

High

547680

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

2

High-throughput

0.536

High

556420

BAG6
Large proline-rich protein BAG6

1

4

High-throughput

0.536

High

556426

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.536

High

556493

MYH13
Myosin-13

1

4

High-throughput

0.536

High

556433

SMAD3
Mothers against decapentaplegic homolog 3

1

2

Small-scale

0.515

High

556447

SMAD2
Mothers against decapentaplegic homolog 2

1

2

Small-scale

0.515

High

556471

ARRD3
Arrestin domain-containing protein 3

1

5

Small-scale

0.515

High

556434

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

556470

P2R3C
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

1

0

High-throughput

0.513

High

556427

IF6
Eukaryotic translation initiation factor 6

1

0

Small-scale

0.504

High

556438

SRBP2
Sterol regulatory element-binding protein 2

1

4

High-throughput

0.494

High

556443

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

6

High-throughput

0.489

High

556454

GXLT1
Glucoside xylosyltransferase 1

1

1

High-throughput

0.489

High

556458

KLC3
Kinesin light chain 3

1

3

High-throughput

0.489

High

556459

BRID5
BRICHOS domain-containing protein 5

1

2

High-throughput

0.489

High

556465

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

4

High-throughput

0.489

High

556472

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

4

High-throughput

0.489

High

556473

MYO19
Unconventional myosin-XIX

1

6

High-throughput

0.489

High

556485

CST11
Cystatin-11

1

4

High-throughput

0.489

High

556425

ATX1
Ataxin-1

1

0

High-throughput

0.486

High

556418

SDC2
Syndecan-2

1

6

Small-scale

0.481

High

205006

TGON2
Trans-Golgi network integral membrane protein 2

1

15

High-throughput

0.479

High

304714

S1PR2
Sphingosine 1-phosphate receptor 2

1

8

Small-scale

0.479

High

521209

SKI
Ski oncogene

1

2

Small-scale

0.479

High

556408

LEG3
Galectin-3

1

18

Small-scale

0.479

High

556412

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

3

Small-scale

0.479

High

556419

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

10

High-throughput

0.479

High

556421

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

556432

X3CL1
Fractalkine

1

3

Small-scale

0.479

High

556468

LPAR1
Lysophosphatidic acid receptor 1

1

6

Small-scale

0.479

High

556475

S1PR3
Sphingosine 1-phosphate receptor 3

1

6

Small-scale

0.479

High

556483

KRA24
Keratin-associated protein 2-4

1

19

High-throughput

0.470

High

556442

ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

1

0

Small-scale

0.458

High

473

NBPFJ
Neuroblastoma breakpoint family member 19

1

7

High-throughput

0.439

High

473262

KRA23
Keratin-associated protein 2-3

1

19

High-throughput

0.439

High

556478

KRA98
Keratin-associated protein 9-8

1

19

High-throughput

0.439

High

556489

SE1L1
Protein sel-1 homolog 1

1

12

Small-scale

0.437

High

556469

AP2C
Transcription factor AP-2 gamma

1

2

High-throughput

0.417

High

556439

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.407

High

556428

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

556449

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.316

High

556451

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

556453

KR151
Keratin-associated protein 15-1

2

0

High-throughput

0.316

High

556476

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

556477

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.316

High

556450

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

556464

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

556486

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.279

Low

556491

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low

556452

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

556460

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

556487

ANLN
Anillin

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024