HitPredict

Interactor 1: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2

Interactor 2: COMA1 (Q8NFW1)
Collagen alpha-1(XXII) chain
Gene: COL22A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 660 Hs			1 1626
+	Hs
		384231 MMP2_HUMAN (1-660): 0: 909: 100.00		CO2A1_HUMAN (711-1624): 5.52e-96: 343: 35.71
+	Hs
		469654 MMP2_HUMAN (1-660): 0: 909: 100.00		CO4A2_HUMAN (221-784): 1.85e-47: 189: 22.48
+	Hs
		384239 MMP9_HUMAN (21-660): 0: 709: 44.17		CO2A1_HUMAN (711-1624): 5.52e-96: 343: 35.71
+	Hs
		384297 MMP2_HUMAN (1-660): 0: 909: 100.00		CO4A1_HUMAN (219-668): 5.08e-29: 129: 17.93
+	Hs
		469674 MMP2_HUMAN (1-660): 0: 909: 100.00		COGA1_HUMAN (222-949): 6.99e-23: 109: 26.04
+	Hs
		469655 MMP2_HUMAN (1-660): 0: 909: 100.00		COBA1_HUMAN (481-966): 3.18e-18: 94: 43.07
+	Hs
		469677 MMP2_HUMAN (1-660): 0: 909: 100.00		CO4A6_HUMAN (1345-1626): 3.26e-18: 93.8: 31.89
+	Hs
		384090 MMP2_HUMAN (1-660): 0: 909: 100.00		CO1A1_HUMAN (219-653): 7.09e-18: 92.7: 22.53
+	Hs
		469662 MMP2_HUMAN (1-660): 0: 909: 100.00		CO5A1_HUMAN (234-677): 1.55e-14: 81.9: 17.20
+	Hs
		469673 MMP2_HUMAN (1-660): 0: 909: 100.00		COEA1_HUMAN (1521-1624): 1.11e-12: 75.7: 30.16
+	Hs
		465926 MMP2_HUMAN (1-660): 0: 909: 100.00		CO1A2_HUMAN (221-466): 1.31e-10: 68.8: 5.69
+	Hs
		438023 MMP2_HUMAN (1-660): 0: 909: 100.00		CO5A2_HUMAN (210-464): 2.96e-09: 64.2: 6.28
+	Hs
		469694 MMP2_HUMAN (1-660): 0: 909: 100.00		COCA1_HUMAN (1185-1301): 4.3e-09: 63.8: 38.81
+	Hs
		471579 MMP9_HUMAN (21-660): 0: 709: 44.17		CO4A2_HUMAN (221-784): 1.85e-47: 189: 22.48
+	Hs
		384300 MMP9_HUMAN (21-660): 0: 709: 44.17		CO4A1_HUMAN (219-668): 5.08e-29: 129: 17.93
+	Hs
		575778 MMP9_HUMAN (21-660): 0: 709: 44.17		CO5A1_HUMAN (234-677): 1.55e-14: 81.9: 17.20
+	Hs
		575787 MMP9_HUMAN (21-660): 0: 709: 44.17		COEA1_HUMAN (1521-1624): 1.11e-12: 75.7: 30.16
+	Hs
		465931 MMP9_HUMAN (21-660): 0: 709: 44.17		CO1A2_HUMAN (221-466): 1.31e-10: 68.8: 5.69
+	Hs
		575802 MMP9_HUMAN (21-660): 0: 709: 44.17		COCA1_HUMAN (1185-1301): 4.3e-09: 63.8: 38.81
+	Hs
		465927 MMP3_HUMAN (18-229): 9.57e-89: 286: 44.95		CO1A2_HUMAN (221-466): 1.31e-10: 68.8: 5.69