HitPredict

Interactor 1: CFAH (P08603)
Complement factor H (H factor 1)
Gene: CFH

Interactor 2: BMP1 (P13497)
Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
Gene: BMP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34943047
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CUB~Sushi, EGF_CA~Sushi
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006508 - proteolysis
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1231 Hs			1 986
+	Hs
		644586 TENX_HUMAN (16-434): 2.74e-43: 175: 13.70		PCOC1_HUMAN (864-983): 9.2e-27: 116: 32.50
+	Ce
		112156 LEV9_CAEEL (233-745): 1.88e-38: 155: 16.33		G5EDX3_CAEEL (770-978): 1.21e-27: 122: 20.85
+	Hs
		1219222 SUSD4_HUMAN (1048-1228): 4.1e-19: 94.2: 16.23		PCOC2_HUMAN (864-980): 2.56e-24: 108: 23.93
+	Hs
		467043 DAF_HUMAN (1-142): 7.5e-19: 92.2: 19.05		ST14_HUMAN (601-871): 1.13e-17: 90.7: 20.71
+	Hs
		444679 CO2_HUMAN (449-624): 3.72e-17: 89.1: 16.75		MASP1_HUMAN (867-981): 1.2e-17: 90.3: 20.80
+	Hs
		1490437 JAG2_HUMAN (416-1102): 4.33e-16: 86.2: 10.37		ST14_HUMAN (601-871): 1.13e-17: 90.7: 20.71
+	Hs
		125802 CO2_HUMAN (449-624): 3.72e-17: 89.1: 16.75		MASP2_HUMAN (870-981): 3.89e-15: 82.1: 24.59
+	Hs
		1369119 PCSK5_HUMAN (203-1213): 1.34e-11: 71.5: 10.40		ST14_HUMAN (601-871): 1.13e-17: 90.7: 20.71
+	Hs
		444674 CO2_HUMAN (449-624): 3.72e-17: 89.1: 16.75		C1S_HUMAN (317-432): 5.32e-12: 72: 19.67
+	Dm
		95089 NOTCH_DROME (428-1071): 9.24e-19: 95: 11.35		E1JHA6_DROME (475-780): 1.49e-09: 64.4: 12.84