HitPredict

Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 354 Hs			1 894
+	Hs
		444699 GNAI3_HUMAN (1-354): 1.47e-176: 495: 100.00		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		580464 GNAT2_HUMAN (1-354): 3.7e-167: 471: 69.49		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		580414 GNAZ_HUMAN (1-353): 7.65e-156: 443: 67.23		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		872647 GNA13_HUMAN (2-353): 2.06e-152: 435: 38.33		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Rn
		444646 GNAI3_RAT (1-354): 4.47e-175: 491: 98.59		INSR_RAT (276-851): 1.26e-134: 437: 27.83
+	Mm
		554960 GNAQ_MOUSE (1-353): 7.93e-162: 458: 51.41		MET_MOUSE (536-799): 5.47e-66: 243: 45.90
+	Mm
		250847 GNAZ_MOUSE (1-353): 2.48e-156: 444: 66.95		MET_MOUSE (536-799): 5.47e-66: 243: 45.90
+	Hs
		444721 GNAI3_HUMAN (1-354): 1.47e-176: 495: 100.00		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		507941 GNAI1_HUMAN (1-354): 4.65e-179: 502: 93.79		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435603 GNAI1_HUMAN (1-354): 4.65e-179: 502: 93.79		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07