HitPredict

Interactor 1: INSR (P09208)
Insulin-like receptor (dIR) (dInr) (dmIR) (EC 2.7.10.1) (Insulin receptor homolog) (dIRH) (Receptor protein-tyrosine kinase InR) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1 (Insulin-like receptor subunit beta 170 kDa form) (beta170); Insulin-like receptor subunit beta 2 (Insulin-like receptor subunit beta 90 kDa form) (beta90); 60 kDa C-terminal fragment (Insulin-like receptor free C-terminus)]
Gene: InR

Interactor 2: P91634 (P91634)
phosphatidylinositol 3-kinase (EC 2.7.1.137)
Gene: Pi3K92E

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 22028469, 27626673
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006979 - response to oxidative stress
GO:0008286 - insulin receptor signaling pathway
GO:0009267 - cellular response to starvation
and 18 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Dm

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Last updated: 11Aug2025