HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: RSF1 (Q96T23)
Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)
Gene: RSF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.668

Property	Details
Experiments	29721183, 31694235, 32867128
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 1441
+	Hs
		659285 SP100_HUMAN (25-178): 7.58e-34: 129: 87.66		RSF1_HUMAN (13-1441): 1.86e-171: 553: 100.00
+	Hs
		1065381 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		RSF1_HUMAN (13-1441): 1.86e-171: 553: 100.00
+	Hs
		1384426 SOX7_HUMAN (65-181): 1.31e-28: 112: 19.66		PF21A_HUMAN (402-1004): 2.25e-67: 243: 15.05
+	Hs
		318524 TOX4_HUMAN (91-163): 1.2e-27: 111: 38.36		PF21A_HUMAN (402-1004): 2.25e-67: 243: 15.05
+	Hs
		481303 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		659173 SP100_HUMAN (25-178): 7.58e-34: 129: 87.66		MYH9_HUMAN (265-1324): 2.5e-38: 159: 10.69
+	Hs
		773125 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MYH10_HUMAN (277-1341): 9.77e-46: 183: 10.59
+	Hs
		1065384 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		UHRF1_HUMAN (654-1274): 9.38e-39: 158: 13.05
+	Hs
		1065234 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		1065160 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		CHD3_HUMAN (475-1062): 1.63e-36: 153: 14.78
+	Hs
		481364 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		UHRF2_HUMAN (882-986): 2.34e-24: 112: 27.03
+	Hs
		687287 HMGB2_HUMAN (1-187): 7.94e-42: 142: 82.89		UHRF2_HUMAN (882-986): 2.34e-24: 112: 27.03
+	Hs
		481343 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		TITIN_HUMAN (351-1406): 6.29e-16: 86.3: 9.92
+	Hs
		318455 TOX4_HUMAN (91-163): 1.2e-27: 111: 38.36		KDM5C_HUMAN (754-972): 3.89e-26: 119: 20.89
+	Hs
		1065374 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		UHRF2_HUMAN (882-986): 2.34e-24: 112: 27.03
+	Hs
		1338269 SOX7_HUMAN (65-181): 1.31e-28: 112: 19.66		KMT2C_HUMAN (830-1420): 8.11e-19: 95.9: 11.64
+	Hs
		1065198 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		CHD4_HUMAN (877-960): 3.85e-14: 80.1: 28.57
+	Hs
		161508 SOX7_HUMAN (65-181): 1.31e-28: 112: 19.66		KMT2D_HUMAN (881-1008): 1.91e-10: 68.1: 21.88
+	Mm
		1222137 Q60I23_MOUSE (3-94): 1.01e-24: 100: 23.91		CHD4_MOUSE (877-960): 6.02e-14: 79.7: 28.57
+	Hs
		161431 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		KMT2D_HUMAN (881-1008): 1.91e-10: 68.1: 21.88