HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: LRC32 (Q14392)
Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32)
Gene: LRRC32

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 662
+	Hs
		502292 BIP_HUMAN (19-654): 0: 914: 100.00		LRC33_HUMAN (26-651): 3.78e-93: 304: 35.40
+	Hs
		502503 BIP_HUMAN (19-654): 0: 914: 100.00		LGR4_HUMAN (176-656): 7.85e-46: 177: 21.64
+	Hs
		871764 HSP72_HUMAN (25-636): 0: 905: 64.51		LGR4_HUMAN (176-656): 7.85e-46: 177: 21.64
+	At
		612329 HS701_ARATH (28-654): 0: 916: 61.46		BRL2_ARATH (1-238): 3.53e-27: 119: 20.99
+	Hs
		501762 BIP_HUMAN (19-654): 0: 914: 100.00		ALS_HUMAN (322-634): 1.1e-27: 120: 23.46
+	Hs
		502531 BIP_HUMAN (19-654): 0: 914: 100.00		NYX_HUMAN (54-218): 6.89e-09: 60.5: 32.45