HitPredict

Interactor 1: VSIG8 (P0DPA2)
V-set and immunoglobulin domain-containing protein 8
Gene: VSIG8

Interactor 2: IL31R (Q8NI17)
Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17)
Gene: IL31RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ig_3~fn3, V-set~fn3
Common GO terms	GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 732
+	Hs
		1270281 BT2A1_HUMAN (17-316): 2.35e-43: 160: 14.29		OSMR_HUMAN (16-727): 1.37e-79: 276: 17.57
+	Hs
		1406220 VSIG4_HUMAN (27-249): 6.69e-14: 74.6: 20.94		OSMR_HUMAN (16-727): 1.37e-79: 276: 17.57
+	Hs
		928840 TITIN_HUMAN (123-388): 5.46e-09: 60.5: 13.46		MYOM2_HUMAN (31-638): 1.56e-67: 244: 12.46
+	Hs
		522686 BT2A1_HUMAN (17-316): 2.35e-43: 160: 14.29		PTPRF_HUMAN (16-344): 2.66e-27: 121: 14.46
+	Hs
		1004244 CXAR_HUMAN (3-397): 3.27e-59: 198: 26.54		FND3A_HUMAN (5-245): 1.01e-14: 80.4: 12.30
+	Hs
		1361883 TITIN_HUMAN (123-388): 5.46e-09: 60.5: 13.46		NEO1_HUMAN (23-725): 3.05e-58: 216: 12.33
+	Hs
		71383 HECA2_HUMAN (5-290): 7.42e-15: 78.1: 17.97		PTPRS_HUMAN (4-731): 1.85e-51: 196: 11.65
+	Hs
		841571 PXDN_HUMAN (96-413): 7.41e-36: 142: 13.10		I12R1_HUMAN (25-582): 2.75e-26: 116: 17.71
+	Hs
		249220 ROBO1_HUMAN (13-404): 1.24e-28: 120: 11.93		DSCAM_HUMAN (20-501): 3.14e-23: 108: 15.25
+	Mm
		564880 NCAM1_MOUSE (9-403): 1.22e-36: 144: 12.26		DSCAM_MOUSE (234-514): 5.22e-13: 75.2: 21.43
+	Hs
		71377 HECA2_HUMAN (5-290): 7.42e-15: 78.1: 17.97		PTPRF_HUMAN (16-344): 2.66e-27: 121: 14.46
+	Rn
		236995 ROBO1_RAT (13-404): 3.44e-27: 116: 11.70		DCC_RAT (6-123): 9.94e-10: 64.5: 14.63
+	Dm
		357180 Q9VMN6_DROME (27-349): 2.74e-20: 95.2: 10.46		SDK_DROME (24-501): 4.12e-16: 85.3: 15.66
+	Mm
		1229941 CNTN4_MOUSE (16-387): 1.78e-21: 99.1: 12.00		CNTN4_MOUSE (2-725): 8.38e-12: 70.8: 8.33
+	Hs
		1198260 TITIN_HUMAN (123-388): 5.46e-09: 60.5: 13.46		FND3B_HUMAN (340-651): 7.81e-19: 93.8: 13.44
+	Ce
		145091 UNC89_CAEEL (11-259): 1.85e-09: 62: 9.88		UNC22_CAEEL (2-113): 6.68e-15: 81.6: 14.78
+	Hs
		1361879 TITIN_HUMAN (123-388): 5.46e-09: 60.5: 13.46		TITIN_HUMAN (4-442): 1.67e-09: 63.9: 10.44