HitPredict

Interactor 1: B2Y833 (B2Y833)
TMPRSS2-ERG prostate cancer specific isoform 1
Gene: ERG

Interactor 2: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.50	0.442

Property	Details
Experiments	21575865
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 220 Hs			1 732
+	Hs
		507356 ERG_HUMAN (1-216): 3.26e-91: 277: 100.00		XRCC5_HUMAN (1-732): 0: 755: 100.00
+	Hs
		524778 ETS1_HUMAN (86-219): 3.29e-48: 165: 28.78		XRCC5_HUMAN (1-732): 0: 755: 100.00
+	Hs
		71382 B2Y833_HUMAN (1-220): 3.65e-101: 293: 100.00		XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49
+	Hs
		507355 ERG_HUMAN (1-216): 3.26e-91: 277: 100.00		XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49
+	Hs
		523492 ETS1_HUMAN (86-219): 3.29e-48: 165: 28.78		XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49