HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: FCG2B (P31994)
Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)
Gene: FCGR2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 310
+	Hs
		522812 SRC_HUMAN (1-536): 0: 651: 100.00		FCG2C_HUMAN (1-310): 1.99e-62: 202: 83.92
+	Hs
		412047 FYN_HUMAN (1-536): 0: 598: 68.39		FCG2B_HUMAN (1-310): 7.03e-74: 231: 100.00
+	Hs
		412048 FYN_HUMAN (1-536): 0: 598: 68.39		FCG2C_HUMAN (1-310): 1.99e-62: 202: 83.92
+	Hs
		523211 SRC_HUMAN (1-536): 0: 651: 100.00		TUTLB_HUMAN (2-304): 6.34e-33: 130: 15.73
+	Hs
		433610 LYN_HUMAN (1-531): 0: 532: 52.44		FCG2B_HUMAN (1-310): 7.03e-74: 231: 100.00
+	Hs
		433507 YES_HUMAN (1-536): 0: 604: 73.85		TUTLB_HUMAN (2-304): 6.34e-33: 130: 15.73
+	Hs
		433545 LYN_HUMAN (1-531): 0: 532: 52.44		FCG2A_HUMAN (38-310): 3.57e-58: 191: 73.29
+	Hs
		411560 LCK_HUMAN (75-534): 0: 552: 58.48		FCG3A_HUMAN (38-272): 1.15e-50: 169: 36.93
+	Hs
		523003 SRC_HUMAN (1-536): 0: 651: 100.00		MYLK_HUMAN (49-129): 7.38e-12: 68.3: 13.83
+	Hs
		519400 SRC_HUMAN (1-536): 0: 651: 100.00		FCERA_HUMAN (2-133): 1.62e-12: 68.2: 16.06
+	Hs
		434111 LYN_HUMAN (1-531): 0: 532: 52.44		ROBO1_HUMAN (2-252): 1.27e-43: 161: 14.44
+	Mm
		435878 HCK_MOUSE (1-531): 0: 564: 54.51		FCGR1_MOUSE (5-304): 1.63e-24: 104: 16.09
+	Mm
		639452 LYN_MOUSE (1-531): 0: 535: 52.26		FCRL5_MOUSE (5-253): 1.79e-34: 133: 19.33
+	Hs
		434081 LYN_HUMAN (1-531): 0: 532: 52.44		TUTLB_HUMAN (2-304): 6.34e-33: 130: 15.73
+	Hs
		442771 HCK_HUMAN (1-531): 0: 569: 55.22		FCGR1_HUMAN (5-285): 9.76e-21: 92.9: 12.25
+	Dm
		219802 ABL_DROME (13-536): 3.26e-173: 532: 38.53		O44924_DROME (2-167): 3.27e-25: 107: 16.11
+	Hs
		434019 LYN_HUMAN (1-531): 0: 532: 52.44		ROBO2_HUMAN (2-125): 1.59e-22: 99.8: 15.91
+	Hs
		433569 LYN_HUMAN (1-531): 0: 532: 52.44		CD22_HUMAN (92-310): 1.59e-09: 60.9: 13.33
+	Hs
		789014 TEC_HUMAN (83-528): 6.43e-155: 458: 37.36		TUTLB_HUMAN (2-304): 6.34e-33: 130: 15.73