HitPredict

Interactor 1: RPA1 (P10964)
DNA-directed RNA polymerase I subunit RPA190 (EC 2.7.7.6) (DNA-directed RNA polymerase I 190 kDa polypeptide) (A190) (DNA-directed RNA polymerase I largest subunit)
Gene: RPA190

Interactor 2: STH1 (P32597)
Nuclear protein STH1/NPS1 (EC 3.6.4.12) (ATP-dependent helicase STH1) (Chromatin structure-remodeling complex protein STH1) (SNF2 homolog)
Gene: STH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16782880
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb1_1~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1664 Sc			1 1359
+	Hs
		243494 RPA1_HUMAN (1-1660): 0: 1572: 35.59		SMCA5_HUMAN (366-1302): 0: 666: 29.97
+	Mm
		107118 RPA1_MOUSE (9-1660): 0: 1574: 35.52		ERCC6_MOUSE (2-1214): 0: 657: 19.33
+	Sc
		401937 RPB1_YEAST (9-1661): 0: 1195: 21.76		STH1_YEAST (1-1359): 0: 978: 100.00
+	Hs
		667465 RPB1_HUMAN (9-1662): 0: 1406: 22.39		CHD8_HUMAN (78-1202): 0: 701: 23.89
+	Dm
		402258 RPB1_DROME (4-1662): 0: 1429: 22.90		BRM_DROME (1068-1357): 4.5e-24: 112: 14.48
+	Hs
		667219 RPB1_HUMAN (9-1662): 0: 1406: 22.39		SMCA4_HUMAN (960-1357): 3.4e-30: 132: 12.28
+	Mm
		476221 RPB1_MOUSE (9-1662): 0: 1406: 22.39		SMCA4_MOUSE (1060-1357): 3.07e-28: 126: 14.77
+	Hs
		667218 RPB1_HUMAN (9-1662): 0: 1406: 22.39		SMCA2_HUMAN (1086-1358): 9.36e-26: 118: 13.78
+	Sc
		402204 RPC1_YEAST (7-237): 1.66e-48: 192: 17.72		STH1_YEAST (1-1359): 0: 978: 100.00