HitPredict

Interactor 1: NHP6B (P11633)
Non-histone chromosomal protein 6B
Gene: NHP6B

Interactor 2: ISW1 (P38144)
ISWI chromatin-remodeling complex ATPase ISW1 (EC 3.6.4.-)
Gene: ISW1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 99 Sc			1 1129
+	Mm
		1222147 Q60I23_MOUSE (2-98): 2.97e-30: 110: 21.65		SMCA5_MOUSE (74-1095): 0: 912: 47.08
+	Hs
		243573 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		SMCA5_HUMAN (74-1095): 0: 908: 46.98
+	Mm
		59403 Q60I23_MOUSE (2-98): 2.97e-30: 110: 21.65		CHD7_MOUSE (25-1121): 0: 841: 26.71
+	Hs
		1434979 SOX17_HUMAN (1-98): 1.57e-30: 113: 25.51		CHD7_HUMAN (25-1121): 0: 837: 26.71
+	Hs
		1413236 SOX7_HUMAN (9-98): 3.61e-30: 111: 25.56		CHD7_HUMAN (25-1121): 0: 837: 26.71
+	Hs
		872830 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		CHD7_HUMAN (25-1121): 0: 837: 26.71
+	Hs
		872559 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		CHD6_HUMAN (25-1101): 0: 812: 26.33
+	Hs
		872266 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		CHD3_HUMAN (8-1120): 0: 810: 25.75
+	Hs
		776181 SOX6_HUMAN (3-98): 5.33e-28: 107: 22.92		CHD3_HUMAN (8-1120): 0: 810: 25.75
+	Hs
		872764 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		CHD8_HUMAN (26-1116): 0: 806: 26.45
+	Hs
		872382 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		CHD9_HUMAN (26-1115): 0: 793: 24.89
+	Hs
		872336 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		CHD4_HUMAN (8-1127): 0: 783: 25.90
+	Mm
		1222137 Q60I23_MOUSE (2-98): 2.97e-30: 110: 21.65		CHD4_MOUSE (8-991): 0: 780: 28.11
+	Mm
		873009 SOX2_MOUSE (2-98): 6.72e-30: 109: 21.65		CHD4_MOUSE (8-991): 0: 780: 28.11
+	Mm
		872983 SOX2_MOUSE (2-98): 6.72e-30: 109: 21.65		SMCA4_MOUSE (6-942): 0: 708: 28.15
+	Hs
		872090 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		SMCA4_HUMAN (128-942): 0: 700: 31.38
+	Hs
		903470 SOX7_HUMAN (9-98): 3.61e-30: 111: 25.56		SMCA4_HUMAN (128-942): 0: 700: 31.38
+	Hs
		903252 SOX17_HUMAN (1-98): 1.57e-30: 113: 25.51		SMCA2_HUMAN (164-652): 1.8e-126: 425: 45.05
+	Hs
		872089 SOX2_HUMAN (20-98): 1.92e-30: 111: 26.58		SMCA2_HUMAN (164-652): 1.8e-126: 425: 45.05
+	Hs
		903246 SOX7_HUMAN (9-98): 3.61e-30: 111: 25.56		SMCA2_HUMAN (164-652): 1.8e-126: 425: 45.05