HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: TAF7 (Q15545)
Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55)
Gene: TAF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

The method score is based on:

Property	Details
Experiments	32076268, 15960975
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0006357 - regulation of transcription by RNA polymerase II and 3 others more... GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0045893 - positive regulation of DNA-templated transcription GO:0071339 - MLL1 complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	334
Hs

1	349

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024