HitPredict

Interactor 1: FCGR1 (P12314)
High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
Gene: FCGR1A

Interactor 2: CRKL (P46109)
Crk-like protein
Gene: CRKL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	9820532
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 374 Hs			1 303
+	Rn
		531970 NCAM1_RAT (2-370): 7.52e-55: 195: 14.81		PLCG1_RAT (5-253): 6.42e-29: 118: 15.85
+	Mm
		564873 NCAM1_MOUSE (2-370): 1.2e-53: 192: 15.15		PLCG1_MOUSE (5-253): 7.99e-29: 118: 15.85
+	Hs
		564796 NCAM1_HUMAN (2-370): 9.12e-53: 189: 15.07		PLCG1_HUMAN (5-253): 8.29e-28: 115: 16.60
+	Hs
		731817 FCG2C_HUMAN (101-287): 6.14e-29: 116: 16.58		CRK_HUMAN (3-302): 1.42e-51: 173: 54.89
+	Hs
		731807 FCG2B_HUMAN (101-287): 1.28e-28: 115: 16.58		CRK_HUMAN (3-302): 1.42e-51: 173: 54.89
+	Mm
		770698 CD22_MOUSE (19-307): 1.13e-29: 122: 17.07		PLCG1_MOUSE (5-253): 7.99e-29: 118: 15.85
+	Hs
		618996 FCG2C_HUMAN (101-287): 6.14e-29: 116: 16.58		PLCG1_HUMAN (5-253): 8.29e-28: 115: 16.60
+	Hs
		618995 FCG2B_HUMAN (101-287): 1.28e-28: 115: 16.58		PLCG1_HUMAN (5-253): 8.29e-28: 115: 16.60
+	Hs
		553393 FCG2A_HUMAN (101-290): 1.32e-31: 123: 15.79		GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89
+	Mm
		770697 CD22_MOUSE (19-307): 1.13e-29: 122: 17.07		GRB2_MOUSE (126-295): 2.84e-23: 97.2: 15.89
+	Hs
		731818 FCG2C_HUMAN (101-287): 6.14e-29: 116: 16.58		GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89
+	Hs
		731809 FCG2B_HUMAN (101-287): 1.28e-28: 115: 16.58		GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89
+	Hs
		913671 TITIN_HUMAN (7-123): 4.74e-09: 60.5: 15.75		VAV2_HUMAN (14-180): 4.48e-40: 150: 19.80
+	Hs
		593927 FCG2C_HUMAN (101-287): 6.14e-29: 116: 16.58		NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81
+	Hs
		593926 FCG2B_HUMAN (101-287): 1.28e-28: 115: 16.58		NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81
+	Hs
		618969 CD22_HUMAN (19-321): 8.67e-09: 59.3: 19.24		PLCG1_HUMAN (5-253): 8.29e-28: 115: 16.60
+	Hs
		987544 PGBM_HUMAN (188-330): 9.81e-10: 62.4: 14.87		GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89
+	Hs
		987664 MYLK_HUMAN (10-105): 1.34e-09: 62.1: 14.02		GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89
+	Hs
		222178 FCRL2_HUMAN (24-196): 1.06e-09: 61.6: 18.04		NCK2_HUMAN (13-98): 9.64e-18: 84.4: 29.89
+	Hs
		594010 MYLK_HUMAN (10-105): 1.34e-09: 62.1: 14.02		NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81