Protein: FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32)

Gene: FCG2A, FCGR2A
Organism: Homo sapiens
Interactions: 47
UniProt ID: P12318

Gene Ontology (top 5):
GO:0001788 - antibody-dependent cellular cytotoxicity
GO:0005886 - plasma membrane
GO:0007166 - cell surface receptor signaling pathway
GO:0009897 - external side of plasma membrane
GO:0019770 - IgG receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

553386

FCG2B
Low affinity immunoglobulin gamma Fc region receptor II-b

3

17

High-throughput

0.861

High

553387

FCG2C
Low affinity immunoglobulin gamma Fc region receptor II-c

3

18

High-throughput

0.861

High

553389

KSYK
Tyrosine-protein kinase SYK

4

20

Small-scale

0.686

High

553395

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

20

High-throughput

0.667

High

553400

PLSI
Plastin-1

3

4

High-throughput

0.667

High

553415

TES
Testin

2

3

High-throughput

0.628

High

553394

CANB1
Calcineurin subunit B type 1

3

1

High-throughput

0.609

High

139176

UPK2
Uroplakin-2

2

2

High-throughput

0.606

High

553383

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

7

Small-scale

0.595

High

553384

BLVRB
Flavin reductase

2

0

High-throughput

0.585

High

162154

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.580

High

553385

MIP
Lens fiber major intrinsic protein

2

0

High-throughput

0.580

High

553396

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.580

High

553401

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

553416

UBQL1
Ubiquilin-1

1

4

High-throughput

0.573

High

553402

EEA1
Early endosome antigen 1

2

11

High-throughput

0.558

High

553409

FAH2A
Oxaloacetate tautomerase FAHD2A, mitochondrial

2

1

High-throughput

0.558

High

463301

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.554

High

553404

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.553

High

553408

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

1

High-throughput

0.553

High

553413

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

1

High-throughput

0.553

High

388489

CRP

1

6

Small-scale

0.553

High

553410

CHM4A
Charged multivesicular body protein 4a

1

1

High-throughput

0.536

High

340611

STABP
STAM-binding protein

1

0

High-throughput

0.513

High

384619

CRYAB
Alpha-crystallin B chain

1

4

Small-scale

0.512

High

553380

LEG3
Galectin-3

1

3

Small-scale

0.501

High

553407

EFHD2
EF-hand domain-containing protein D2

1

3

High-throughput

0.489

High

138441

BIN1
Myc box-dependent-interacting protein 1

1

2

Small-scale

0.479

High

220346

LAT
Linker for activation of T-cells family member 1

1

1

Small-scale

0.479

High

553379

ITA4
Integrin alpha-4

1

10

High-throughput

0.479

High

553397

Q08AM2
ADAM33 protein

1

8

High-throughput

0.470

High

553411

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

3

High-throughput

0.439

High

553381

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

Small-scale

0.437

High

553392

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

2

High-throughput

0.437

High

553399

NFYC
Nuclear transcription factor Y subunit gamma

1

1

High-throughput

0.437

High

553393

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.408

High

553382

APEX1
DNA repair nuclease/redox regulator APEX1

3

0

High-throughput

0.347

High

321077

PLPHP
Pyridoxal phosphate homeostasis protein

2

0

High-throughput

0.318

High

553390

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

2

0

High-throughput

0.318

High

553391

BID
BH3-interacting domain death agonist

2

0

High-throughput

0.318

High

553412

PRDC1
Phosphoribosyltransferase domain-containing protein 1

2

0

High-throughput

0.318

High

553388

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.316

High

553405

SERP2
Stress-associated endoplasmic reticulum protein 2

2

0

High-throughput

0.316

High

553406

GIMA1
GTPase IMAP family member 1

2

0

High-throughput

0.316

High

553398

SCRN1
Secernin-1

1

0

High-throughput

0.279

Low

553403

ARPIN
Arpin

1

0

High-throughput

0.249

Low

553414

ADPRS
ADP-ribosylhydrolase ARH3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025