Protein: FCG2B
Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)

Gene: FCG2B, FCGR2B
Organism: Homo sapiens
Interactions: 25
UniProt ID: P31994

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001788 - antibody-dependent cellular cytotoxicity
GO:0001811 - negative regulation of type I hypersensitivity
GO:0001814 - negative regulation of antibody-dependent cellular cytotoxicity
GO:0001818 - negative regulation of cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

553386

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

3

17

High-throughput

0.861

High

379219

IGHG1
Immunoglobulin heavy constant gamma 1

1

8

Small-scale

0.692

High

731813

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

5

8

Small-scale

0.692

High

711039

PTN6
Tyrosine-protein phosphatase non-receptor type 6

3

18

Small-scale

0.656

High

731810

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

17

Small-scale

0.639

High

731808

GSK3A
Glycogen synthase kinase-3 alpha

3

5

High-throughput

0.609

High

463367

LYN
Tyrosine-protein kinase Lyn

2

15

Small-scale

0.585

High

711249

SHC1
SHC-transforming protein 1

2

20

Small-scale

0.571

High

731809

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.563

High

618995

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

3

High-throughput

0.561

High

439661

INSR
Insulin receptor

1

12

High-throughput

0.515

High

603181

KPCA
Protein kinase C alpha type

1

3

Small-scale

0.501

High

703453

MK01
Mitogen-activated protein kinase 1

1

6

Small-scale

0.501

High

609593

LEG3
Galectin-3

1

2

Small-scale

0.500

High

256446

TOM1
Target of Myb1 membrane trafficking protein

1

2

Small-scale

0.479

High

440403

FYN
Tyrosine-protein kinase Fyn

1

15

High-throughput

0.479

High

557129

SRC
Proto-oncogene tyrosine-protein kinase Src

1

15

High-throughput

0.479

High

593926

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

731807

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

731814

KLK6
Kallikrein-6

1

4

High-throughput

0.470

High

258590

SH21A
SH2 domain-containing protein 1A

1

20

Small-scale

0.437

High

731811

GAB1
GRB2-associated-binding protein 1

1

3

Small-scale

0.373

High

731815

SYMM
Methionine--tRNA ligase, mitochondrial

3

0

High-throughput

0.347

High

731812

CRYM
Ketimine reductase mu-crystallin

1

0

High-throughput

0.279

Low

731816

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025