HitPredict

Interactor 1: NR4A1 (P12813)
Nuclear receptor subfamily 4 group A member 1 (Nuclear hormone receptor NUR/77) (Nuclear protein N10) (Orphan nuclear receptor HMR)
Gene: NR4A1

Interactor 2: HDAC6 (Q9Z2V5)
Protein deacetylase HDAC6 (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) (mHDA2)
Gene: HDAC6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19321449
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Mm			1 1149
+	Hs
		652594 NR4A1_HUMAN (1-601): 8.52e-143: 428: 90.18		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		652511 NR4A1_HUMAN (1-601): 8.52e-143: 428: 90.18		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Mm
		148658 RXRA_MOUSE (131-597): 1.26e-111: 343: 26.81		HDAC1_MOUSE (470-870): 1.52e-156: 476: 20.75
+	Hs
		396057 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		396641 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC2_HUMAN (77-488): 7.68e-156: 475: 21.89
+	Hs
		940943 NR1H3_HUMAN (179-594): 5.85e-115: 351: 27.15		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Mm
		148699 ERR2_MOUSE (173-597): 2.45e-105: 326: 27.10		HDAC1_MOUSE (470-870): 1.52e-156: 476: 20.75
+	Hs
		396590 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC7_HUMAN (439-886): 3.69e-144: 460: 36.82
+	Mm
		1000012 ERR2_MOUSE (173-597): 2.45e-105: 326: 27.10		HDAC2_MOUSE (77-488): 6.66e-155: 472: 21.89
+	Hs
		395773 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Hs
		625791 RXRA_HUMAN (126-597): 1.98e-110: 340: 26.53		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Hs
		520575 RARA_HUMAN (187-598): 2.66e-102: 319: 28.33		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		520611 RARA_HUMAN (187-598): 2.66e-102: 319: 28.33		HDAC2_HUMAN (77-488): 7.68e-156: 475: 21.89
+	Hs
		397244 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC5_HUMAN (439-878): 9.05e-140: 453: 35.89
+	Hs
		188156 THB_HUMAN (267-597): 1e-114: 351: 28.33		HDAC3_HUMAN (478-909): 2e-142: 437: 18.24
+	Hs
		397188 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC9_HUMAN (441-827): 1.34e-136: 441: 37.89
+	Hs
		188143 ESR1_HUMAN (89-595): 1.21e-108: 340: 23.54		HDAC3_HUMAN (478-909): 2e-142: 437: 18.24
+	Hs
		188169 RXRA_HUMAN (126-597): 1.98e-110: 340: 26.53		HDAC3_HUMAN (478-909): 2e-142: 437: 18.24
+	Hs
		520543 RARA_HUMAN (187-598): 2.66e-102: 319: 28.33		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Hs
		188153 RARA_HUMAN (187-598): 2.66e-102: 319: 28.33		HDAC3_HUMAN (478-909): 2e-142: 437: 18.24