Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: PDLI4 (P50479)
PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein)
Gene: PDLIM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments unassigned1304
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~LIM
Common GO terms GO:0001725 - stress fiber
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030018 - Z disc
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 892
Hs

1 330
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Mm
+ Mm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025