HitPredict

Interactor 1: ACTN (P18091)
Alpha-actinin, sarcomeric (F-actin cross-linking protein)
Gene: ACTN

Interactor 2: Q95TZ7 (Q95TZ7)
GH19182p (Z band alternatively spliced PDZ-motif protein 66, isoform F)
Gene: Zasp66

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	23505387, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0030018 - Z disc GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 924 Dm			1 402
+	Dm
		612387 ACTN_DROME (1-924): 0: 628: 100.00		Q8IQB4_DROME (14-402): 4.75e-93: 288: 93.06
+	Mm
		1274482 ACTN1_MOUSE (5-924): 0: 623: 67.28		PDLI5_MOUSE (5-372): 2.72e-51: 182: 16.75
+	Hs
		270701 ACTN1_HUMAN (5-924): 0: 623: 67.50		LDB3_HUMAN (7-277): 2.97e-45: 168: 19.85
+	Hs
		555669 ACTN1_HUMAN (5-924): 0: 623: 67.50		ZO1_HUMAN (2-383): 7.61e-42: 159: 14.57
+	Hs
		123214 ACTN1_HUMAN (5-924): 0: 623: 67.50		PDLI1_HUMAN (8-253): 1.11e-38: 143: 17.00
+	Rn
		1231096 ACTN1_RAT (5-924): 0: 626: 67.50		PDLI2_RAT (9-265): 3.3e-36: 137: 21.37
+	Hs
		555767 ACTN1_HUMAN (5-924): 0: 623: 67.50		PDLI7_HUMAN (5-232): 9.11e-37: 140: 19.39
+	Hs
		555639 ACTN1_HUMAN (5-924): 0: 623: 67.50		PDLI4_HUMAN (13-246): 1.59e-35: 134: 23.01
+	Hs
		270703 ACTN2_HUMAN (5-924): 0: 576: 66.41		LDB3_HUMAN (7-277): 2.97e-45: 168: 19.85
+	Dm
		56341 ACTN_DROME (1-924): 0: 628: 100.00		ZASP_DROME (18-124): 4.76e-27: 115: 33.03
+	Hs
		555760 ACTN1_HUMAN (5-924): 0: 623: 67.50		SYP2L_HUMAN (5-248): 7.96e-28: 118: 18.51
+	Mm
		1440839 ACTN2_MOUSE (5-924): 0: 579: 66.52		LDB3_MOUSE (7-277): 1.41e-38: 149: 19.05
+	Hs
		123242 ACTN3_HUMAN (21-924): 0: 580: 66.04		PDLI1_HUMAN (8-253): 1.11e-38: 143: 17.00
+	Hs
		773748 ACTN2_HUMAN (5-924): 0: 576: 66.41		PDLI3_HUMAN (11-238): 9.55e-40: 147: 17.15
+	Hs
		123228 ACTN2_HUMAN (5-924): 0: 576: 66.41		PDLI1_HUMAN (8-253): 1.11e-38: 143: 17.00
+	Hs
		773790 ACTN2_HUMAN (5-924): 0: 576: 66.41		PDLI7_HUMAN (5-232): 9.11e-37: 140: 19.39
+	Hs
		1061559 ACTN3_HUMAN (21-924): 0: 580: 66.04		SYP2L_HUMAN (5-248): 7.96e-28: 118: 18.51
+	Hs
		555742 ACTN1_HUMAN (5-924): 0: 623: 67.50		MAGI1_HUMAN (14-367): 1.81e-12: 71.3: 12.01
+	Hs
		773786 ACTN2_HUMAN (5-924): 0: 576: 66.41		SYP2L_HUMAN (5-248): 7.96e-28: 118: 18.51
+	Mm
		1365316 ACTN2_MOUSE (5-924): 0: 579: 66.52		GRIP1_MOUSE (9-100): 4.63e-11: 66.6: 22.34