HitPredict

Interactor 1: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Interactor 2: Q9W2J2 (Q9W2J2)
Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform A
Gene: ASPP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30770806
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 302 Dm			1 1020
+	Hs
		967717 PP1A_HUMAN (2-301): 0: 549: 92.67		ASPP2_HUMAN (13-1017): 2.34e-92: 320: 28.33
+	Mm
		98307 PP1A_MOUSE (2-301): 0: 550: 92.33		E9QJU8_MOUSE (13-1017): 2.36e-91: 317: 28.80
+	Hs
		967682 PP1A_HUMAN (2-301): 0: 549: 92.67		Q05BL1_HUMAN (13-1017): 2.55e-91: 316: 28.42
+	Mm
		968099 PP1A_MOUSE (2-301): 0: 550: 92.33		IASPP_MOUSE (249-1014): 7.88e-70: 251: 20.63
+	Hs
		967876 PP1A_HUMAN (2-301): 0: 549: 92.67		IASPP_HUMAN (249-1014): 1.92e-61: 227: 20.41
+	Hs
		967728 PP1A_HUMAN (2-301): 0: 549: 92.67		KANK1_HUMAN (36-940): 1.97e-57: 218: 13.31
+	Hs
		967671 PP1A_HUMAN (2-301): 0: 549: 92.67		ANK2_HUMAN (650-1017): 7.96e-47: 186: 15.10
+	Mm
		968117 PP1A_MOUSE (2-301): 0: 550: 92.33		ASPP1_MOUSE (22-842): 9.86e-39: 158: 16.78
+	Hs
		967833 PP1A_HUMAN (2-301): 0: 549: 92.67		PPR27_HUMAN (810-926): 1.24e-39: 145: 32.20
+	Hs
		967916 PP1A_HUMAN (2-301): 0: 549: 92.67		ASPP1_HUMAN (19-842): 1.3e-34: 145: 15.02
+	Hs
		967914 PP1A_HUMAN (2-301): 0: 549: 92.67		PP16A_HUMAN (829-927): 3.07e-19: 94.6: 36.36
+	Hs
		967936 PP1A_HUMAN (2-301): 0: 549: 92.67		PP16B_HUMAN (835-927): 8.52e-18: 90.3: 35.48
+	Hs
		171216 PP1A_HUMAN (2-301): 0: 549: 92.67		MYPT1_HUMAN (829-949): 6.64e-14: 78.4: 30.33
+	Mm
		968206 PP1A_MOUSE (2-301): 0: 550: 92.33		MYPT1_MOUSE (847-949): 1.74e-13: 77.2: 33.98
+	Mm
		989704 PP1G_MOUSE (3-301): 0: 549: 93.31		MYPT1_MOUSE (847-949): 1.74e-13: 77.2: 33.98
+	Mm
		968091 PP1A_MOUSE (2-301): 0: 550: 92.33		PP12C_MOUSE (821-926): 6.74e-12: 71.8: 30.63
+	Hs
		967953 PP1A_HUMAN (2-301): 0: 549: 92.67		PP12C_HUMAN (821-924): 2.6e-11: 69.9: 29.36
+	Mm
		968132 PP1A_MOUSE (2-301): 0: 550: 92.33		MYPT2_MOUSE (829-925): 1.14e-09: 64.5: 27.55
+	Hs
		239307 PP1A_HUMAN (2-301): 0: 549: 92.67		MYPT2_HUMAN (829-925): 7.67e-10: 65.3: 27.55
+	Hs
		772713 PP1A_HUMAN (2-301): 0: 549: 92.67		MYH9_HUMAN (3-735): 3.89e-09: 63.3: 9.56