HitPredict

Interactor 1: K1C10 (P13645)
Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)
Gene: KRT10

Interactor 2: PERI (P41219)
Peripherin (Neurofilament 4)
Gene: PRPH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005737 - cytoplasm GO:0005882 - intermediate filament GO:0016020 - membrane GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 584 Hs			1 470
+	Hs
		833254 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		PERI_HUMAN (1-470): 3.75e-165: 475: 100.00
+	Hs
		474626 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		VIME_HUMAN (10-458): 3.82e-146: 427: 56.79
+	Hs
		474439 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		VIME_HUMAN (10-458): 3.82e-146: 427: 56.79
+	Hs
		437152 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C8_HUMAN (12-456): 3.41e-140: 412: 33.54
+	Hs
		437075 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		K2C8_HUMAN (12-456): 3.41e-140: 412: 33.54
+	Hs
		606105 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		DESM_HUMAN (56-462): 7.23e-129: 383: 62.26
+	Hs
		566095 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		DESM_HUMAN (56-462): 7.23e-129: 383: 62.26
+	Hs
		1047491 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		KRT84_HUMAN (22-430): 2.32e-98: 309: 32.12
+	Hs
		566222 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		KRT84_HUMAN (22-430): 2.32e-98: 309: 32.12
+	Hs
		1047431 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C79_HUMAN (4-418): 6.07e-86: 275: 31.83
+	Hs
		341758 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C75_HUMAN (4-410): 7.71e-85: 272: 33.73
+	Hs
		341731 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		K2C75_HUMAN (4-410): 7.71e-85: 272: 33.73
+	Hs
		1047416 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C72_HUMAN (9-410): 9.72e-79: 255: 30.30
+	Hs
		566362 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C5_HUMAN (62-410): 6.91e-72: 240: 35.98
+	Hs
		566093 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		K2C5_HUMAN (62-410): 6.91e-72: 240: 35.98
+	Hs
		407275 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C6B_HUMAN (62-410): 1.61e-71: 238: 34.56
+	Hs
		876459 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C6C_HUMAN (62-410): 1.48e-71: 238: 34.56
+	Hs
		407245 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		K2C6B_HUMAN (62-410): 1.61e-71: 238: 34.56
+	Hs
		385261 K1C17_HUMAN (140-456): 6.24e-150: 440: 70.03		K2C6A_HUMAN (62-410): 2.1e-70: 235: 34.56
+	Hs
		385229 K1C10_HUMAN (141-454): 1.7e-147: 439: 100.00		K2C6A_HUMAN (62-410): 2.1e-70: 235: 34.56