HitPredict

Interactor 1: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Interactor 2: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.913

The method score is based on:

Property Details
Experiments 29859926, 9630597, 30021884, 35575683, 28524877
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, cross-linking study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0045111 - intermediate filament cytoskeleton
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 483
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025