Interactor 1: DCAM (P17707)
S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]
Gene: AMD1
Interactor 2: DCAM (P17707)
S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]
Gene: AMD1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.69 | 1.00 | 0.836 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 10378277, unassigned1304 |
| Identification Methods | two hybrid, x-ray crystallography, two hybrid array, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SAM_decarbox~SAM_decarbox |
| Common GO terms | GO:0004014 - adenosylmethionine decarboxylase activity GO:0005829 - cytosol GO:0006595 - polyamine metabolic process GO:0006597 - spermine biosynthetic process GO:0008295 - spermidine biosynthetic process and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Dm |   |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Pf |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
