HitPredict

Interactor 1: HCLS1 (P14317)
Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75)
Gene: HCLS1

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12534372
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 Hs			1 418
+	Mm
		1221192 SRC8_MOUSE (1-486): 8.97e-129: 386: 40.88		ARP3_MOUSE (1-418): 0: 588: 99.76
+	Hs
		958101 SRC8_HUMAN (1-486): 1.09e-127: 383: 39.86		ARP3_HUMAN (1-418): 0: 588: 100.00
+	Hs
		952816 SRC8_HUMAN (1-486): 1.09e-127: 383: 39.86		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		993176 SRC8_HUMAN (1-486): 1.09e-127: 383: 39.86		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		995590 SRC8_HUMAN (1-486): 1.09e-127: 383: 39.86		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Dm
		1014448 Q9VDF4_DROME (1-485): 1.5e-100: 314: 35.79		ACT6_DROME (3-414): 0: 530: 34.87
+	Hs
		386459 SPTA1_HUMAN (32-485): 6.82e-59: 212: 15.34		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Hs
		952809 SPTN1_HUMAN (32-486): 2.51e-44: 169: 14.41		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		993169 SPTN1_HUMAN (32-486): 2.51e-44: 169: 14.41		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Dm
		534413 SPTCA_DROME (33-486): 1.01e-42: 164: 12.93		ACT1_DROME (3-414): 0: 534: 35.35
+	Dm
		534342 SPTCA_DROME (33-486): 1.01e-42: 164: 12.93		ACT5_DROME (3-414): 0: 533: 35.35
+	Hs
		996450 SPTN1_HUMAN (32-486): 2.51e-44: 169: 14.41		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Dm
		386970 SPTCA_DROME (33-486): 1.01e-42: 164: 12.93		ACT2_DROME (3-414): 0: 532: 35.11
+	Hs
		995581 SPTN1_HUMAN (32-486): 2.51e-44: 169: 14.41		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Dm
		561565 SPTCA_DROME (33-486): 1.01e-42: 164: 12.93		ACT3_DROME (3-414): 0: 531: 35.35
+	Dm
		561567 SPTCA_DROME (33-486): 1.01e-42: 164: 12.93		ACT6_DROME (3-414): 0: 530: 34.87
+	Dm
		387023 SPTCA_DROME (33-486): 1.01e-42: 164: 12.93		ACT4_DROME (3-414): 0: 526: 35.35
+	Sc
		948648 MYO5_YEAST (90-484): 8.7e-40: 155: 12.41		ACT_YEAST (1-414): 0: 528: 34.94
+	Hs
		635507 NEBU_HUMAN (145-485): 2.78e-35: 142: 16.03		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Sc
		865586 MYO5_YEAST (90-484): 8.7e-40: 155: 12.41		ARP3_YEAST (6-417): 1.14e-171: 489: 58.35