HitPredict

Interactor 1: ACT1 (P10987)
Actin-5C (EC 3.6.4.-)
Gene: Act5C

Interactor 2: SPTCA (P13395)
Spectrin alpha chain
Gene: alpha-Spec

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29249285
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~EF-hand_7
Common GO terms	GO:0030723 - ovarian fusome organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Dm			1 2415
+	Dm
		534342 ACT5_DROME (1-376): 0: 605: 96.81		SPTCA_DROME (1-2415): 0: 619: 100.00
+	Dm
		386970 ACT2_DROME (1-376): 0: 604: 99.47		SPTCA_DROME (1-2415): 0: 619: 100.00
+	Dm
		561565 ACT3_DROME (1-376): 0: 603: 96.28		SPTCA_DROME (1-2415): 0: 619: 100.00
+	Dm
		561567 ACT6_DROME (1-376): 0: 603: 96.01		SPTCA_DROME (1-2415): 0: 619: 100.00
+	Hs
		1143145 ACTBL_HUMAN (1-376): 0: 733: 90.69		PLEC_HUMAN (1-1338): 7.59e-40: 166: 8.88
+	Hs
		540248 ACTB_HUMAN (1-376): 0: 603: 97.61		SPTB1_HUMAN (237-1897): 9.89e-71: 267: 20.33
+	Hs
		953067 ACTB_HUMAN (1-376): 0: 603: 97.61		CP250_HUMAN (331-2403): 3.45e-69: 262: 9.08
+	Hs
		174729 ACTB_HUMAN (1-376): 0: 603: 97.61		SPTN2_HUMAN (9-1560): 3.16e-61: 236: 18.96
+	Hs
		952750 ACTB_HUMAN (1-376): 0: 603: 97.61		SPTB2_HUMAN (5-1707): 1.15e-58: 228: 19.92
+	Hs
		993135 ACTG_HUMAN (3-376): 0: 603: 98.13		SPTB2_HUMAN (5-1707): 1.15e-58: 228: 19.92
+	Hs
		952809 ACTB_HUMAN (1-376): 0: 603: 97.61		SPTN1_HUMAN (2-1232): 6.72e-45: 182: 21.48
+	Hs
		993169 ACTG_HUMAN (3-376): 0: 603: 98.13		SPTN1_HUMAN (2-1232): 6.72e-45: 182: 21.48
+	Hs
		952834 ACTB_HUMAN (1-376): 0: 603: 97.61		PLEC_HUMAN (1-1338): 7.59e-40: 166: 8.88
+	Hs
		993183 ACTG_HUMAN (3-376): 0: 603: 98.13		PLEC_HUMAN (1-1338): 7.59e-40: 166: 8.88
+	Hs
		953184 ACTB_HUMAN (1-376): 0: 603: 97.61		MACF1_HUMAN (477-2365): 5.17e-23: 110: 9.15
+	Hs
		952759 ACTB_HUMAN (1-376): 0: 603: 97.61		DYST_HUMAN (732-2397): 1.4e-22: 109: 9.22
+	Hs
		993139 ACTG_HUMAN (3-376): 0: 603: 98.13		DYST_HUMAN (732-2397): 1.4e-22: 109: 9.22
+	Dm
		534344 ACT5_DROME (1-376): 0: 605: 96.81		ACTN_DROME (678-1113): 1.62e-18: 95.1: 14.44
+	Hs
		224675 ACTB_HUMAN (1-376): 0: 603: 97.61		ACTN4_HUMAN (1821-2158): 1.76e-13: 78.6: 22.87
+	Hs
		773720 ACTB_HUMAN (1-376): 0: 603: 97.61		ACTN2_HUMAN (1983-2260): 1.83e-09: 65.5: 23.63