HitPredict

Interactor 1: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Interactor 2: PTPRE (P49446)
Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48)
Gene: PTPRE

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12376545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Y_phosphatase~Y_phosphatase
Common GO terms	GO:0004725 - protein tyrosine phosphatase activity GO:0016311 - dephosphorylation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 829 Mm			1 699
+	Mm
		574008 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRD_MOUSE (1-696): 0: 899: 42.31
+	Mm
		69645 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRS_MOUSE (1-696): 0: 891: 41.33
+	Mm
		56906 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRF_MOUSE (2-696): 0: 880: 42.05
+	Hs
		576983 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRE_HUMAN (1-699): 0: 891: 92.73
+	Mm
		573997 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRA_MOUSE (25-699): 0: 848: 64.02
+	Hs
		576980 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRA_HUMAN (22-699): 0: 863: 66.23
+	Hs
		616971 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRD_HUMAN (1-696): 0: 895: 42.31
+	Hs
		616939 PTPRD_HUMAN (14-827): 0: 885: 37.97		PTPRD_HUMAN (1-696): 0: 895: 42.31
+	Mm
		828098 PTPRD_MOUSE (14-827): 0: 890: 37.85		PTPRE_MOUSE (1-699): 0: 890: 100.00
+	Mm
		69646 PTPRS_MOUSE (5-827): 0: 887: 36.26		PTPRE_MOUSE (1-699): 0: 890: 100.00
+	Hs
		1031977 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRS_HUMAN (1-696): 0: 886: 41.27
+	Hs
		489957 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRF_HUMAN (2-696): 0: 875: 41.90
+	Hs
		576984 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRG_HUMAN (421-697): 8.51e-101: 339: 33.92
+	Hs
		616916 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRB_HUMAN (335-691): 4.03e-112: 374: 30.94
+	Mm
		574010 PTPRA_MOUSE (1-829): 0: 1004: 100.00		S4R1M0_MOUSE (119-452): 3.5e-71: 253: 26.56
+	Mm
		573998 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRM_MOUSE (112-397): 3.78e-65: 236: 32.66
+	Hs
		577029 PTPRA_HUMAN (1-829): 0: 973: 89.50		Q5VWH6_HUMAN (1-139): 1.2e-60: 201: 82.27
+	Mm
		69654 PTPRS_MOUSE (5-827): 0: 887: 36.26		S4R1M0_MOUSE (119-452): 3.5e-71: 253: 26.56