HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: MBD6 (Q96DN6)
Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6)
Gene: MBD6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36180891
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 1003
+	Rn
		92877 CTNB1_RAT (1-731): 2.15e-172: 516: 67.38		D3ZCX1_RAT (1-1003): 1.11e-88: 308: 88.64
+	Hs
		577598 PLAK_HUMAN (1-745): 0: 550: 100.00		MUC1_HUMAN (119-980): 1.87e-40: 164: 14.30
+	Hs
		590252 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		MUC1_HUMAN (119-980): 1.87e-40: 164: 14.30
+	Hs
		577915 PLAK_HUMAN (1-745): 0: 550: 100.00		MBD5_HUMAN (1-547): 6.86e-27: 121: 25.57
+	Mm
		811944 CTNB1_MOUSE (1-731): 6.44e-172: 514: 67.38		ZO1_MOUSE (80-834): 9.33e-30: 130: 11.04
+	Hs
		764694 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		ZO1_HUMAN (80-834): 1.18e-26: 120: 12.32
+	Dm
		616637 ARM_DROME (2-730): 2.02e-160: 487: 60.33		Q9VPR2_DROME (58-593): 4.92e-13: 75.3: 11.75
+	Hs
		911046 IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32		MBD6_HUMAN (1-1003): 1e-98: 335: 100.00
+	Hs
		254045 CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25		MUC1_HUMAN (119-980): 1.87e-40: 164: 14.30
+	Hs
		911138 IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32		CHD7_HUMAN (179-726): 7.56e-32: 137: 13.43
+	Hs
		911136 IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32		MBD5_HUMAN (1-547): 6.86e-27: 121: 25.57
+	Hs
		138713 IMA4_HUMAN (228-670): 1.86e-63: 222: 15.79		ANR11_HUMAN (16-751): 1.53e-13: 77.6: 13.09
+	Hs
		253645 IMA7_HUMAN (266-685): 6.6e-45: 171: 15.27		ANR11_HUMAN (16-751): 1.53e-13: 77.6: 13.09