HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: IMB1 (P52296)
Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: Kpnb1

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0019899 - enzyme binding GO:0044877 - protein-containing complex binding GO:0051879 - Hsp90 protein binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 875
+	Rn
		94177 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		IMB1_RAT (1-875): 0: 629: 100.00
+	Hs
		497032 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		IMB1_HUMAN (1-875): 0: 634: 98.52
+	Hs
		1056831 MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08		IMB1_HUMAN (1-875): 0: 634: 98.52
+	Hs
		312169 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		IPO7_HUMAN (3-847): 8.48e-78: 275: 11.38
+	Hs
		497394 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TNPO1_HUMAN (99-869): 8.76e-31: 132: 11.70
+	Hs
		155519 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TNPO2_HUMAN (163-868): 5.68e-29: 126: 13.31
+	Hs
		127171 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		IPO5_HUMAN (3-610): 7.43e-12: 71.5: 11.16
+	Hs
		127176 MUC1_HUMAN (5-652): 3.87e-39: 158: 12.50		IPO5_HUMAN (3-610): 7.43e-12: 71.5: 11.16
+	Hs
		268682 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		SF3B1_HUMAN (2-730): 5.19e-25: 114: 14.65
+	Dm
		1370249 Q9VLS7_DROME (3-541): 3.66e-12: 72.4: 11.77		Q9VPR5_DROME (2-763): 1.23e-16: 87.3: 10.44