HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2871 Hs			1 427
+	Hs
		587809 DESP_HUMAN (1-2871): 0: 839: 100.00		WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89
+	Hs
		587723 DESP_HUMAN (1-2871): 0: 839: 100.00		WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53
+	Hs
		587645 DESP_HUMAN (1-2871): 0: 839: 100.00		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		587609 DESP_HUMAN (1-2871): 0: 839: 100.00		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		587585 DESP_HUMAN (1-2871): 0: 839: 100.00		LIS1_HUMAN (8-187): 2.44e-32: 128: 8.08
+	Hs
		587823 DESP_HUMAN (1-2871): 0: 839: 100.00		NLE1_HUMAN (279-427): 9.16e-31: 125: 16.77
+	Hs
		587613 DESP_HUMAN (1-2871): 0: 839: 100.00		GBB2_HUMAN (217-427): 6.3e-19: 89.3: 15.57
+	Hs
		1143269 PLEC_HUMAN (2198-2814): 5.42e-32: 140: 34.90		WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89
+	Hs
		1117486 SPTN1_HUMAN (235-2163): 9.1e-27: 123: 10.31		WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89
+	Hs
		964954 GOGB1_HUMAN (633-2516): 6.16e-51: 203: 10.49		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		1143222 PLEC_HUMAN (2198-2814): 5.42e-32: 140: 34.90		FBXW7_HUMAN (8-311): 5.97e-65: 222: 11.94
+	Hs
		945863 EPIPL_HUMAN (2625-2847): 9.98e-13: 76.9: 18.52		WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89
+	Hs
		248731 PEPL_HUMAN (427-1469): 2.83e-22: 108: 11.19		WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53
+	Hs
		964961 PLEC_HUMAN (2198-2814): 5.42e-32: 140: 34.90		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		964932 SPTN1_HUMAN (235-2163): 9.1e-27: 123: 10.31		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		845288 CENPE_HUMAN (1148-2593): 3.45e-40: 167: 9.60		LIS1_HUMAN (8-187): 2.44e-32: 128: 8.08
+	Hs
		945764 EPIPL_HUMAN (2625-2847): 9.98e-13: 76.9: 18.52		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		209331 CP250_HUMAN (32-1160): 2.51e-39: 164: 9.05		PRP4_HUMAN (273-421): 1.55e-16: 83.6: 12.67
+	Hs
		965333 MACF1_HUMAN (2583-2820): 1.08e-10: 70.3: 19.25		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		945769 EPIPL_HUMAN (2625-2847): 9.98e-13: 76.9: 18.52		GBB2_HUMAN (217-427): 6.3e-19: 89.3: 15.57